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CAS: 2375419-35-3
英文名称: 
sr-301
sr301
n-(2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-6-(1h-imidazol-1-yl)pyridazine-3-carboxamide
6-(1h-imidazol-1-yl)-n-[2-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3-pyridazinecarboxamide
sr 301
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货号品牌产品名称规格包装、参考价格详情
SML2996Sigma-AldrichSR-301≥98% (HPLC)949.53元/5 MG;   3828.18元/25 MG;   展开

产品说明

生化/生理作用

SR-301 is an orally bioavailable analog of the selective STING agonist SR-717. SR-301 shows higher potency than SR-717 by THP1-based ISRE reporter assay (EC50 = 0.6 vs. 2.1 μM, respectively) and shows good antitumor efficacy when administered orally in a murine B16.F10 melanoma tumor model in vivo (15 mg/kg/day p.o.).

基本信息

经验(实验)分子式C17H11F6N5O2
分子量431.29

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃
SMILES stringO=C(C1=NN=C(N2C=NC=C2)C=C1)NC3=C(C(O)(C(F)(F)F)C(F)(F)F)C=CC=C3
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