CAS 23672-07-3; 左旋舒必利; (S)-(-)-Sulpiride

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货号品牌产品名称规格包装、参考价格详情
S798256MACKLIN(S)-(-)-舒必利10mM in DMSO417元/1ml;   
储存：-20°C
I0821TCI(S)-(-)-Sulpiride>98.0%(T)(HPLC)150元/5G;   430元/25G;   
基本信息
纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C15H23N3O4S = 341.43
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况加热
Reaxys-RN3563418
PubChem物质ID135726922
Merck Index (14)8989
MDL编号MFCD00055220
技术规格
AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 98.0   area%
Purity(Nonaqueous Titration)min. 98.0   %
Melting point185.0   to 189.0    ℃
Specific rotation [a]20/D-67.0 to -71.0 deg(C=3, DMF)
物性(参考值)
熔点187 ℃
比旋光度 [α]D-69° (C=3,DMF)
溶解性(可溶于)二甲基甲酰胺
安全信息
信号词警告
危险性说明H303 : 吞咽可能有害。
防范说明P312 : 如感觉不适，呼叫急救中心/医生。
相关法规
RTECS#BZ3400100
519766J&KLevosulpiride98%, 一种选择性D2多巴胺受体拮抗剂523元/5G;   1577元/25G;   
基本信息
分子式C15H23N3O4S
分子量341.43
熔点185-189
比旋光度([α]20D)-71 to -67 (C=3, DMF)
MDL编码MFCD00055220
Beilstein3563418
Merck14,8989
存储条件Freezer -20℃
产品描述
Levosulpiride是一种选择性D2多巴胺受体拮抗剂，用作抗精神病药和促动力剂。
靶点（IC50 & Targe）
Dopamine
安全信息
图形或危害标志
提示语Warning
危险说明H302
H400
H410
防范说明P264
P270
P273
P301+P312
P330
P391
P501
UN号码3077
危险分类9
包装等级III
WGK3
RTECSBZ3400100
S7771Sigma-Aldrich(S)-(-)-Sulpiride≥98% (titration)1203.82元/5 G;   1746.39元/10 G;   
产品说明
应用
(S)-(−)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11
包装
5, 10 g in poly bottle
生化/生理作用
(S)-(−)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function,  (S)-(−)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9
D2 多巴胺受体拮抗剂；安定药。
特点和优势
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式C15H23N3O4S
分子量341.43
MDL编号MFCD00055220
PubChem化学物质编号24278709
NACRESNA.77
产品性质
质量水平100
测定≥98% (titration)
mp183-186 ℃ (lit.)
创始人Sanofi Aventis
储存温度2-8℃
SMILES stringCCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
InChI1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
InChI keyBGRJTUBHPOOWDU-NSHDSACASA-N
Gene Informationhuman ... DRD2(1813), DRD3(1814)
rat ... Adra1a(29412), Drd2(24318), Drd3(29238), Htr1a(24473), Htr2a(29595)
安全信息
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
34002Supelco(S)-(-)-SulpirideVETRANAL®, analytical standard1292.31元/100 MG;   
产品说明
一般描述
(S)-(−)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.
应用
(S)-(−)-Sulpiride may be used as an analytical reference standard for the determination of the drug, in biological samples using hydrophilic interaction liquid chromatography−tandem mass spectrometry (HILIC−MS/MS) and reversed-phase high-performance liquid chromatography with fluorescence detection (HPLC-FD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
生化/生理作用
D2 多巴胺受体拮抗剂；安定药。
法律信息
VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH
基本信息
经验(实验)分子式C15H23N3O4S
分子量341.43
MDL编号MFCD00055220
PubChem化学物质编号329754747
NACRESNA.24
产品性质
等级analytical standard
质量水平100
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp183-186 ℃ (lit.)
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES stringCCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
InChI1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
InChI keyBGRJTUBHPOOWDU-NSHDSACASA-N
安全信息
储存分类代码10 - Combustible liquids
WGKWGK 3
个人防护装备Eyeshields, Gloves, type N95 (US)