产品说明

应用

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

生化/生理作用

Strong ligand for retinoic acid receptor proteins

特点和优势

LightOx25 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx25 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

其他说明

Chemical Equivalency 1ea=1mg

法律信息

LightOx is a trademark of LightOx Ltd.

基本信息

产品性质

安全信息