CAS 233275-76-8; mk-0343

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CAS:

233275-76-8

分子式:

C₁₉H₁₇F₂N₇O

分子量:

397.38

英文名称:

mk-0343

7-cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1h-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine

mrk-409

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

M897384

MACKLIN

7-环丁基-3-(2,6-二氟苯基)-6-((1-甲基-1H-1,2,4-三唑-5-基)甲氧基)-[1,2,4]三唑并[4,3-b]哒嗪

97%

645元/1mg; 1614元/5mg; 2677元/10mg; 4283元/25mg;

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储存：2-8°C，保存于惰性气体中

SML0565

Sigma-Aldrich

MK-0343

≥98% (HPLC)

5852.13元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

MK-0343 (MRK-409) is a partial agonist for GABAA receptors with comparable Ki values for α1, α2, α3 and α5 containing receptors (0.2 – 0.4 nM). The compound has the greatest agonist activity against α3 receptors, and is brain penatrant, and displays anxiolytic activity in rodent and primate models.

特点和优势

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₉H₁₇F₂N₇O
分子量	397.38
MDL编号	MFCD22683821
PubChem化学物质编号	329825556
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	Cn1ncnc1COc2nn3c(nnc3cc2C4CCC4)-c5c(F)cccc5F
InChI	1S/C19H17F2N7O/c1-27-16(22-10-23-27)9-29-19-12(11-4-2-5-11)8-15-24-25-18(28(15)26-19)17-13(20)6-3-7-14(17)21/h3,6-8,10-11H,2,4-5,9H2,1H3
InChI key	GOIFCXRIFSYPFG-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

500537

Fluorochem

MK 0343

95%

12188元/50mg; 36564元/250mg;

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基本信息

CAS Number	233275-76-8
MDL Number	MFCD22683821

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