[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 23256-42-0
关键词:       仅模糊查询
CAS: 23256-42-0
分子式: C14H18N4O3.C3H6O3
分子量: 380.40
中文名称: 
乳酸甲氧苄啶
乳酸TMP
乳酸甲氧苄氨嘧啶
英文名称: 
trimethoprim lactate
用途: 抗菌药。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T854916MACKLIN甲氧苄啶 乳酸盐95%30元/1g;   48元/5g;   124元/25g;   375元/100g;   1300元/500g;   展开
储存: 2-8°C
状态:白色或浅黄色结晶粉末
T0667Sigma-AldrichTrimethoprim lactate salt≥98%4694.34元/250 MG;   展开

产品说明

一般描述

Chemical structure: pyrimidine

应用

Trimethoprim is primarily used as an antibacterial agent. It has dihydrofolate reductase inhibitor activity with selectivity for the prokaryote enzyme. It is used clinically to treat urinary tract infections, mild acute prostatitis, recurrent cystitis, asymptomatic bacteriuria during pregnancy and respiratory tract infections. Trimethoprim lactate salt is used as a selection agent.

包装

250 mg in glass bottle

生化/生理作用

The combination of trimethoprim and sulfamethoxazole interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to prokaryote-specific dihydrofolate reductase (DHFR) and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis.

其他说明

Keep container tightly closed in a dry and well-ventilated place.

基本信息

经验(实验)分子式C14H18N4O3 · C3H6O3
分子量380.40
EC 号245-533-1
MDL编号MFCD00171722
PubChem化学物质编号329826610
NACRESNA.85

产品性质

质量水平200
测定≥98%
形式powder
储存条件 (Keep container tightly closed in a dry and well-ventilated place.)
颜色 white
溶解性H2O: soluble 20 mg/mL
作用机制DNA synthesis | interferes
enzyme | inhibits
抗生素抗菌谱Gram-negative bacteria
Gram-positive bacteria
mycobacteria
储存温度2-8℃
SMILES stringCC(O)C(O)=O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
InChI1S/C14H18N4O3.C3H6O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-2(4)3(5)6/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2,4H,1H3,(H,5,6)
InChI keyIIZVTUWSIKTFKO-UHFFFAOYSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H361d
预防措施声明P202 - P264 - P270 - P280 - P301 + P310 - P405
危险分类Acute Tox. 3 Oral - Repr. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9