CAS 23256-30-6; thiomorpholine, 3-methyl-4-((5-nitrofurfurylidene)amino)-, 1,1-dioxide

CAS:

23256-30-6

分子式:

C₁₀H₁₃N₃O₅S

分子量:

287.3

英文名称:

thiomorpholine, 3-methyl-4-((5-nitrofurfurylidene)amino)-, 1,1-dioxide

1-((5-nitrofurfurylidene)amino)-2-methyltetrahydro-1,4-thiazine-4,4-diox ide

3-methyl-4-(5'-nitrofurylidene-amino)-tetrahydro-4h-1,4-thiazine-1,1-dio xide

4-((5-nitrofurfurylidene)amino)-3-methylthiomorpholine-1,1-dioxide

bay 2502

bayer 2502

lampit

nifurtimox

tetrahydro-3-methyl-4-((5-nitrofurfurylidene)amino)-2h-1,4-thiazine 1,1-dioxi

用途:

Nifurtimox 是一种用于治疗锥虫病 (Trypanosoma cruzi) 的抗虫剂。Nifurtimox 可用于治疗神经母细胞瘤细胞。Nifurtimox 影响乳酸脱氢酶 (LDH) 活性。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

N880149

MACKLIN

Nifurtimox

≥99%

807元/5mg; 1506元/10mg;

展开

储存：2-8℃

N3415

Sigma-Aldrich

Nifurtimox

≥98% (HPLC)

1515.08元/5 MG; 6095.01元/25 MG;

展开

产品说明

一般描述

Nifurtimox acts as a hypoxia-activated cytotoxin, which specifically kills clonogenic tumor cells under hypoxic conditions. It is used to treat Chagas disease and African trypanosomiasis. Nifurtimox inhibits neuroblastoma and medulloblastoma cell growth.

应用

Nifurtimox has been used in drug treatment in culture media.

包装

5, 25 mg in glass bottle

生化/生理作用

Nifurtimox is a nitrofurane derivative used to treat diseases caused by trypanosomes. Nifurtimox was discovered empirically and its mechanism of action is unclear. It is believed that nifurtimox exerts its biological activity through the bioreduction of the nitro-group to a nitro-anion radical which undergoes redox-cycling with molecular oxygen.

特点和优势

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₁₀H₁₃N₃O₅S
分子量	287.29
EC 号	245-531-0
MDL编号	MFCD00869254
PubChem化学物质编号	329818609
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	yellow to orange
溶解性	DMSO: ≥13 mg/mL
创始人	Bayer
储存温度	room temp
SMILES string	CC1CS(=O)(=O)CCN1\N=C\c2ccc(o2)[N+]([O-])=O
InChI	1S/C10H13N3O5S/c1-8-7-19(16,17)5-4-12(8)11-6-9-2-3-10(18-9)13(14)15/h2-3,6,8H,4-5,7H2,1H3/b11-6+
InChI key	ARFHIAQFJWUCFH-IZZDOVSWSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable