CAS 23052-81-5; l(+)-2-amino-4-phosphonobutyric acid

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CAS:

23052-81-5

分子式:

C4H10NO5P

分子量:

183.10

熔点:

207-215℃

英文名称:

l(+)-2-amino-4-phosphonobutyric acid

用途:

L-APB 是一种有效的、代谢型谷氨酸受体 (mGluR) 的特异性激动剂，其对 mGlu4, mGlu8, mGlu6 和 mGlu7 受体的 EC50 值分别为 0.13, 0.29, 1.0, 249 μM。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

L880169

MACKLIN

L-APB

≥99%

655元/1mg;

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储存：2-8℃

A7929

Sigma-Aldrich

L-(+)-2-Amino-4-phosphonobutyric acid

optical purity optical purity: ≥95% (HPLC, Marfey′s reagent)

1347.84元/0.5 MG; 2208.08元/1 MG;

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产品说明

包装

0.5, 1 mg in glass bottle

生化/生理作用

mGluR₄ 和 mGluR₆ 代谢型谷氨酸受体激动剂。

基本信息

经验(实验)分子式	C₄H₁₀NO₅P
分子量	183.10
MDL编号	MFCD00083244
PubChem化学物质编号	24891296
NACRES	NA.32

产品性质

光学纯度	optical purity: ≥95% (HPLC, Marfey′s reagent)
SMILES string	N[C@@H](CCP(O)(O)=O)C(O)=O
InChI	1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
InChI key	DDOQBQRIEWHWBT-VKHMYHEASA-N
Gene Information	human ... GRM1(2911), GRM2(2912), GRM3(2913), GRM4(2914), GRM6(2916), GRM7(2917), GRM8(2918) rat ... Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

M01257

Fluorochem

L-(+)-2-Amino-4-phosphonobutyric acid

>99%

1342元/5mg; 2442元/10mg; 5148元/25mg; 9416元/50mg;

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基本信息

CAS Number	23052-81-5
MDL Number	MFCD00083244

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .

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