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CAS: 22839-47-0
分子式: C14H18N2O5
分子量: 294.31
熔点: 242-248 °C
中文名称: 
阿斯巴甜
甜乐
甜味素
蛋白糖
N-L-α-天冬氨酰-L-苯丙氨酸甲酯
天冬氨酰苯丙氨酸甲酯
天冬氨酸-苯丙氨酸甲酯
链节,基体
阿司帕坦
L-天冬氨酰-L-苯丙氨酸甲酯
英文名称: 
L-Phenylalanine,N-L-.alpha.-aspartyl-,1-methyl ester
N-L-Aspartyl-L-phenylalanine 1-methyl ester
L-Phenylalanine, N-L-.alpha.-aspartyl-, 1-methyl ester
Aspartame
succinamic acid, 3-amino-n-(alpha-carboxyphenethyl)-, n-methyl ester, stereoiso
mer
1-methyl n-l-alpha-aspartyl-l-phenylalanine
3-amino-n-(alpha-carboxyphenethyl)succinamic acid n-methyl ester
3-amino-n-(alpha-carboxyphenethyl)succinamic acid n-methyl ester, stereoisome
3-amino-n-(alpha-methoxycarbonylphenethyl) succinamic acid
aspartylphenylalanine methyl ester
canderel
dipeptide sweetener
equal
Asp-Phe methyl ester
l-aspartyl-l-phenylalanine methyl ester
n-l- alpha-aspartyl-l-phenylalanin 1-methyl ester
n-l-alpha-aspartyl-l-phenylalanin 1-methyl ester
methyl aspartylphenylalanate
methyl n-l-alpha-aspartyl-l-phenylalaninate
n-l-alpha-aspartyl-l-phenylalanine 1-methyl ester
n-l-alpha-aspartyl-l-phenylalanine, 1-methyl ester
nutrasweet
Asp-Phe-OMe
sc 18862
sweet dipeptide
tri-sweet
succinamic acid, 3-amino-n-(alpha-carboxyphenethyl)-,n-methyl ester, stereoisomer
展开更多英文名
性质描述: 白色结晶性粉末。双熔点约190℃和245℃。微溶于水(约1%)和乙醇(0.26mg/100ml)。无臭、有强烈甜味,其稀溶液的甜度约为蔗糖的100-200倍。其甜味与砂糖十分相似,并有清凉感。0.8%水溶液的pH值为4-6.5。在水溶液中不稳定,易分解而失去甜味,低温时和pH值3-5时较稳定。
生产方法: 由L-天冬氨酸和L-苯丙氨酸甲酯缩合而得。
用途: 按我国GB2760-90规定可用于各类食品,最大使用量视正常生产需要而定。按FAO/WHO(1984)规定,可用于甜食,用量0.3%,胶姆糖1.0%,饮料0.1%,早餐谷物0.5%,以及配制用于糖尿病,高血压、肥胖症、心血管患者的低糖类、低热量保健食品,用量视需要而定。亦可用作风味增强剂。
推荐供应商
货号品牌产品名称规格包装、参考价格
A798444MACKLIN阿斯巴甜10mM in DMSO449元/1ml;   咨询
储存:-20°C
A801109MACKLIN阿斯巴甜98%30元/5g;   38元/25g;   99元/100g;   329元/500g;   1435元/2.5kg;   咨询
储存:2~8°C
状态:白色到浅黄色粉末
折射率:14.5 ° (C=4, 15mol/L Formic Acid)
A0997TCIAspartame>98.0%(T)(HPLC)370元/1G;   1330元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C14H18N2O5 = 294.31
外观与形状(20℃)固体
Reaxys-RN2223850
PubChem物质ID87562491
SDBS (AIST Spectral DB)18099
Merck Index (14)839
MDL编号MFCD00002724

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D+12.0 to +17.0 deg(C=4, 15mol/L Formic acid)
Watermax. 4.5 %

物性(参考值)

比旋光度 [α]D14.5° (C=4,15mol/L Formic Acid)
水溶性实际上不溶

相关法规

RTECS#WM3407000
419216J&KAspartame98%, 用于研究294元/1G;   1075元/5G;   3765元/25G;   咨询

基本信息

分子式C14H18N2O5
分子量294.30
熔点248-250
比旋光度([α]20D)+12.5° to +17.5° (C=4, 15 N formic acid)
MDL编码MFCD00002724
Beilstein2223850
Merck14,839
EINECS 编号245-261-3
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK2
RTECSWM3407000
960614J&KAspartame98%72元/250MG;   239元/1G;   咨询

基本信息

分子式C14H18N2O5
分子量294.30
熔点248-250
比旋光度([α]20D)12.0° to 17.0° (C=4, 15 mol/L Formic acid)
MDL编码MFCD00002724
Beilstein2223850
Merck14,839
EINECS 编号245-261-3
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK2
RTECSWM3407000
C22865Alfa AesarL-Aspartyl-L-phenylalanine methyl ester98%812元/1g;   1981元/5g;   6685元/25g;   咨询

基本信息

Ref#
22865

MDL
2724

分子式
C14 H18 N2 O5

分子量
294.3

PHR1381SupelcoAspartamePharmaceutical Secondary Standard; Certified Reference Material1143.5元/1 G;   咨询

产品说明

一般描述

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
阿斯巴甜是一种低卡路里的营养糖替代品,用于桌面甜味剂、口香糖、软饮料等。

应用

阿斯巴甜可用作药物标准品,用于通过高效液相色谱法测定药物制剂中的分析物。
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

附注

要查看该材料的分析证书示例,请在下面的栏位中输入LRAB9987。这只是一个示例证书,可能不是您收到的批次。

基本信息

线性分子式HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
分子量294.30
Beilstein2223850
EC 号245-261-3
MDL编号MFCD00002724
PubChem化学物质编号329823358
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur A1320000
traceable to USP 1043706
储存温度2-30℃
SMILES stringCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI keyIAOZJIPTCAWIRG-QWRGUYRKSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
W700655Sigma-AldrichAspartame≥98%, FG414.88元/;   580.93元/1 KG;   3322.18元/10 KG;   6644.25元/25 KG;   咨询

产品说明

其他说明

Download our Flavors and Fragrances Catalog to view our entire product line.
Subscribe to our Newsletter to keep up to date on our latest Flavors and Fragrances offerings.

基本信息

线性分子式HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
分子量294.30
Beilstein2223850
MDL编号MFCD00002724
E编号E951

产品性质

质量水平400
等级FG
Halal
Kosher
reg. complianceEU Regulation 1333/2008 & 178/2002
FDA 21 CFR 117
测定≥98%
mp248-250 ℃ (lit.)
文件see Safety & Documentation for available documents
性状检查odorless
application(s)flavors and fragrances
食品过敏原no known allergens
SMILES stringCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI keyIAOZJIPTCAWIRG-QWRGUYRKSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
A1320000AspartameEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 40 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
分子量294.30
Beilstein2223850
MDL编号MFCD00002724
PubChem化学物质编号329770357
NACRESNA.24

产品性质

等级pharmaceutical primary standard
agencyEP Reference Standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI keyIAOZJIPTCAWIRG-QWRGUYRKSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
1043706USPAspartameUnited States Pharmacopeia (USP) Reference Standard3633.89元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
分子量294.30
Beilstein2223850
MDL编号MFCD00002724
PubChem化学物质编号329749070
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI keyIAOZJIPTCAWIRG-QWRGUYRKSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
A5139Sigma-AldrichAsp-Phe methyl ester≥98%669.59元/1 G;   1907.24元/5 G;   咨询

产品说明

一般描述

天冬氨酸-苯丙氨酸甲酯 (aspartame,APM,Asp) 是由苯基丙氨酸和天冬氨酸组成的二肽酯。对其遗传毒性作用进行了研究。研究了其与某些亲水胶体的相互作用。

应用

Asp-Phe 甲酯用于制备 自由采食 标准饲料,以及含 Asp-Phe 甲酯的 自由采食 饮用水(动物控制饲料)。 也用于 TFA 饲料制备(含 和 饮用水的 TFA 饲料含有 Asp-Phe 甲酯)。

包装

1, 5, 25 g in poly bottle

生化/生理作用

Asp-Phe 甲酯 (Asp-Phe-OMe) 被用作合成甜味剂、糖替代品。Asp-Phe 甲酯作为营养补充剂正在进行多种潜在益处的研究,如延缓骨关节炎和调节类风湿因子活性。目前正在研究 Asp-Phe 甲酯对凝血酶活性和凝血的效果。

基本信息

线性分子式HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
分子量294.30
Beilstein2223850
EC 号245-261-3
MDL编号MFCD00002724
PubChem化学物质编号24890947
NACRESNA.26

产品性质

质量水平200
测定≥98%
形式powder
甜味 160-200 × sucrose
颜色 white to off-white
储存温度2-8℃
SMILES stringCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI keyIAOZJIPTCAWIRG-QWRGUYRKSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
47135SupelcoAspartameanalytical standard470.69元/500 MG;   咨询

产品说明

应用

有关合适仪器技术的更多信息,请参考产品 分析证书。如需进一步支持,请联系技术服务。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF47135.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

基本信息

线性分子式HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
分子量294.30
Beilstein2223850
EC 号245-261-3
MDL编号MFCD00002724
PubChem化学物质编号24870725
E编号E951

产品性质

质量水平100
等级analytical standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)cleaning products
cosmetics
food and beverages
personal care
格式neat
储存温度2-8℃
SMILES stringCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI keyIAOZJIPTCAWIRG-QWRGUYRKSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
078978FluorochemAsp-Phe methyl ester98%220元/10g;   264元/100g;   咨询

基本信息

CAS Number22839-47-0
MDL NumberMFCD00002724
Boiling Point535.8 ℃ at 760 mmHg
Melting Point242-248℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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