CAS 227609-66-7; a-278637

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CAS:

227609-66-7

英文名称:

a-278637

(9S)-9-(3-bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-thieno[3,2-b]quinolin-8(4h)-one 1,1-dioxide

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货号

品牌

产品名称

规格

包装、参考价格

SML1033

Sigma-Aldrich

A-278637

≥98%

5343.25元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

A-278637 is a selective opener of ATP-sensitive K (KATP) channels (EC₅₀ = 102 nM) that blocks contraction of bladder smooth muscle in both in vivo and in vitro assays. A-278637 is 15-fold more selective than nifedipine for bladder compared other smooth muscle KATP channels, and displays reduced effects on mean arterial pressure compared to other channel openers.

基本信息

经验(实验)分子式	C₁₇H₁₅BrFNO₃S
分子量	412.27
NACRES	NA.77

产品性质

质量水平	100
测定	≥98%
形式	powder
旋光性	[α]/D -44 to -54°, c = 0.1 in acetonitrile
颜色	white to beige
溶解性	DMSO: 5 mg/mL, clear (warmed)
储存温度	2-8℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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