CAS 223652-90-2; garenoxacin mesylate monohydrate

CAS:

223652-90-2

分子式:

C₂₄H₂₆F₂N₂O₈S

分子量:

540.53

英文名称:

garenoxacin mesylate monohydrate

garenfloxacin mesylate

1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-2,3-dihydro-1-methyl-1h-isoindol-5-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid methane sulfonic acid salt monohydrate

t-3811 mesylate

ganefloxacin mesylate

bms 284756 mesylate

用途:

Garenoxacin Mesylate hydrate (BMS284756 Mesylate hydrate) 是一种新型的口服des-fluoro(6)喹诺酮, 具有强的抗菌活性, 抗常见呼吸道病原体, 包括耐药菌株。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

G880251

MACKLIN

Garenoxacin Mesylate hydrate

≥99%

588元/5mg; 896元/10mg;

咨询

储存：2-8℃

SML1618

Sigma-Aldrich

Garenoxacin mesylate monohydrate

≥98% (HPLC)

1117.23元/10 MG; 4498.97元/50 MG;

咨询

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Garenoxacin is a broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections. Garenoxacin has a low mutant prevention concentration and a narrow mutant selection window. Data shows that garenoxacin has anti-inflammatory properties. It significantly alleviates LPS-induced IL-8 production through the negative regulation of the ERK1/2 pathway both in the human airway epithelial cell line A549 and the monocyte cell line THP-1.

基本信息

经验(实验)分子式	C₂₃H₂₀F₂N₂O₄· CH₄O₃S · H₂O
分子量	540.53
MDL编号	MFCD12031996
PubChem化学物质编号	329825504
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 10 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	OC(C1=CN(C2CC2)C3=C(OC(F)F)C(C4=CC(CN[C@@H]5C)=C5C=C4)=CC=C3C1=O)=O.CS(=O)(O)=O.[H]O[H]
InChI	1S/C23H20F2N2O4.CH4O3S.H2O/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30;1-5(2,3)4;/h2,5-8,10-11,14,23,26H,3-4,9H2,1H3,(H,29,30);1H3,(H,2,3,4);1H2/t11-;;/m1../s1
InChI key	IGTHEWGRXUAFKF-NVJADKKVSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3