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关键词:       仅模糊查询
CAS: 22204-53-1
分子式: C14H14O3
分子量: 230.26
熔点: 152-154 °C(lit.)
中文名称: 
萘普生
消炎宁
消痛灵
甲氧萘丙酸
DL-萘普生
(S)-(+)-2-(6-甲氧基-2-萘基)丙酸
萘普生混旋体
DL萘普生
英文名称: 
(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
Naproxene
(+)-6-Methoxy-à-methyl-2-naphthaleneacetic acid
(S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid
(+)-Naproxen
DL-Naproxen
()-2-(methoxy-2-naphthyl)-propionic acid
()-2-(methoxy-2-naphthyl)-propionsaeure (german)
(+)-2-(methoxy-2-naphthyl)-propionic acid
(+)-2-(methoxy-2-naphthyl)-propionsaeure
(+)-2-(methoxy-2-naphthyl)-propionsaeure (german)
(+)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid
(+)-2-naphthaleneacetic aci
(S)-2-naphthaleneacetic aci
axer
bonyl
calosen
cg 3117
d-2-(6'-methoxy-2'-naphthyl)-propionsaeure
d-2-(6-methoxy-2-naphthyl)propionic acid
d-naproxen
diocodal
dysmenalgit n
equiproxen
floginax
laraflex
naixan
napren e
naprium
naprius
naprosine
naprosyn
naprosyne
naproxen
naprux
naxen
naxyn
prexan
primeral
()-propionic aci
proxen
reuxen
rs-3540
veradol
xenar
6-Methoxy-methyl-2-naphthaleneacetic acid
展开更多英文名
用途: 医药萘普生中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
S824053MACKLIN(S)-(+)-2-(6-甲氧基-2-萘基)丙酸98%30元/5g;   59元/25g;   159元/100g;   750元/500g;   咨询
储存:室温,干燥,密封
状态:白色到灰白色粉末
S795446MACKLIN(S)-(+)-2-(6-甲氧基-2-萘基)丙酸10mM in DMSO431元/1ml;   咨询
储存:-20°C
M1021TCI(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid>99.0%(GC)(T)290元/25G;   2990元/500G;   咨询

基本信息

纯度/分析方法>99.0%(GC)(T)
分子式/分子量C14H14O3 = 230.26
外观与形状(20℃)固体
应避免的情况
Reaxys-RN3591067
PubChem物质ID87572993
SDBS (AIST Spectral DB)19020
Merck Index (14)6417
MDL编号MFCD00010500

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 99.0 %
Purity(Neutralization titration)min. 99.0 %
Melting point155.0 to 158.0 ℃
Specific rotation [a]20/D+65.0 to +70.0 deg(C=1, CHCl3)

物性(参考值)

熔点155 ℃
比旋光度 [α]D67.5° (C=1,CHCl3)
水溶性不溶
溶解性(易溶于)

安全信息

图形或危害标志
信号词危险
危险性说明H301 : 吞咽会中毒。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H361 : 怀疑对生育能力或胎儿造成伤害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P308 + P313 : 如接触到或有疑虑:求医/就诊。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#UF5275000

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
922806J&KNaproxen99%, COX抑制剂90元/1G;   360元/5G;   751元/25G;   5225元/500G;   咨询

基本信息

分子式C14H14O3
分子量230.26
熔点154-156
比旋光度([α]20D)+65 to +70 (C=1, CHCl3)
MDL编码MFCD00010500
Beilstein3591067
Merck14,6417
EINECS 编号244-838-7

安全信息

图形或危害标志
提示语Danger
危险说明H301
H315
H319
H335
防范说明P301+P310
P302+P352
P305+P351+P338
P321
P405
P501A
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSUF5275000
919368J&KNaproxen99%68元/1G;   271元/5G;   1019元/25G;   咨询

基本信息

分子式C14H14O3
分子量230.26
熔点154-156
比旋光度([α]20D)+65 to +70 (C=1, CHCl3)
MDL编码MFCD00010500
Beilstein3591067
Merck14,6417
EINECS 编号244-838-7

安全信息

图形或危害标志
提示语Danger
危险说明H301
H315
H319
H335
防范说明P301+P310
P302+P352
P305+P351+P338
P321
P405
P501A
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSUF5275000
L09855Alfa Aesar(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid99%282元/1g;   844元/5g;   1635元/25g;   咨询

应用
(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid is a non-selective cyclooxygenase (COX-1 and COX-2) inhibitor.

备注
Store at room temperature. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00010500

EINECS
244-838-7

分子式
C14H14O3

分子量
230.26

熔点
154-156°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Insoluble in water.

Beilstein
3591067

Merck
14,6417

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H315-H319-H335
Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
III

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
UF5275000

TSCA

R10985Alfa AesarNaproxen Standard solution100ppm210元/1ml;   咨询

安全信息

危险等级
3

284785Sigma-Aldrich(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid98%740.97元/5 G;   928.41元/25 G;   咨询

产品说明

一般描述

(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid is a nonsteroidal anti-inflammatory molecule (NSAID). The (S)-enantiomer is 30 times more active than the (R)-enantiomer.

应用

(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid can be used as a chiral ligand in the synthesis of organotin (IV) carboxylate metal complexes.

包装

5, 25 g in poly bottle

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
EC 号244-838-7
MDL编号MFCD00010500
PubChem化学物质编号24857178
NACRESNA.22

产品性质

质量水平200
测定98%
旋光性[α]25/D +66°, c = 1 in chloroform
mp152-154 ℃ (lit.)
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... MAPK14(1432), PTGS1(5742), PTGS2(5743)
rat ... Alox5(25290), Ptgs1(24693)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
46482SupelcoNaproxenVETRANAL®, analytical standard1006.19元/250 MG;   咨询

产品说明

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
EC 号244-838-7
MDL编号MFCD00010500
PubChem化学物质编号329757200
NACRESNA.24

产品性质

质量水平200
等级analytical standard
agencyEPA 1694
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp152-154 ℃ (lit.)
application(s)clinical
environmental
forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
N8280Sigma-AldrichNaproxenmeets USP testing specifications967.79元/5 G;   咨询

产品说明

包装

5 g in glass bottle

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
EC 号244-838-7
MDL编号MFCD00010500
PubChem化学物质编号24897861
NACRESNA.21

产品性质

质量水平200
agencyUSP/NF
meets USP testing specifications
形式powder
mp152-154 ℃ (lit.)
application(s)pharmaceutical (small molecule)
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... MAPK14(1432), PTGS1(5742), PTGS2(5743)
rat ... Alox5(25290), Ptgs1(24693)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
PHR1040SupelcoNaproxenPharmaceutical Secondary Standard; Certified Reference Material1631.37元/500 MG;   咨询

产品说明

一般描述

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
萘普生是芳基乙酸类化合物,可用作非甾体类抗炎药 (NSAID)。它可用于治疗疼痛、炎症和僵硬。它还可用于治疗类风湿关节炎和其他肌肉骨骼疼痛症。

应用

这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
萘普生 (Naproxen) 可用作药物参考标准品,用于通过高效液相色谱 (HPLC) 技术测定药物制剂中的分析物。

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

分析说明

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。所有关于该CRM的信息都可以在分析证书上找到。

附注

要查看该材料的分析证书示例,请在下面的栏位中输入 LRAA8968。这只是一个示例证书,可能不是您收到的批次。

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
EC 号244-838-7
MDL编号MFCD00010500
PubChem化学物质编号329823070
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp152-154 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 435
traceable to PhEur N0250000
traceable to USP 1457301
储存温度2-30℃
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
1457301USPNaproxenUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
MDL编号MFCD00010500
PubChem化学物质编号329750529
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp152-154 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
N0250000NaproxenEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
MDL编号MFCD00010500
PubChem化学物质编号329818408
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp152-154 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
BP435NaproxenBritish Pharmacopoeia (BP) Reference Standard1861.35元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

非选择性环加氧酶(COX-1 和 COX-2)抑制剂。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

线性分子式CH3OC10H6CH(CH3)CO2H
分子量230.26
Beilstein3591068
EC 号244-838-7
MDL编号MFCD00010500
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp152-154 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringCOc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
InChI1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChI keyCMWTZPSULFXXJA-VIFPVBQESA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H315 - H319 - H335 - H361fd
预防措施声明P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
079426Fluorochem(S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid98%220元/1g;   242元/10g;   572元/25g;   1760元/100g;   咨询

基本信息

CAS Number22204-53-1
MDL NumberMFCD00010500

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H361fd: Reproductive toxicity
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P362: Take off contaminated clothing and wash before reuse.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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