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CAS: 218795-74-5
英文名称: 
imm-01
n1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide
2-[(2,4-dihydroxyphenyl)methylene]-n-(1,1-dimethylethyl)-hydrazinecarbothioamide
intramimic-01
推荐供应商
货号品牌产品名称规格包装、参考价格
SML1064Sigma-AldrichIMM-01≥98% (HPLC)1396.09元/5 MG;   4498.97元/25 MG;   咨询

产品说明

应用

IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs).

包装

5, 25 mg in glass bottle

生化/生理作用

IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer.
IMM-01 binds and activates formin thereby leading to autoinhinition.

基本信息

经验(实验)分子式C12H17N3O2S
分子量267.35
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to light brown
溶解性DMSO: 10 mg/mL, clear
储存温度2-8℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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