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CAS: 2149-70-4
分子式: C6H13N5O4
分子量: 219.20
熔点: 257-260℃
英文名称: 
n(sup 5)-(imino(nitroamino)methyl)-l-ornithin
(+)-nc-nitroarginine
l-ng-nitroarginine
n5-[imino(nitroamino)methyl]-l-ornithin
n(sup 5)-(imino(nitroamino)methyl)-l-ornithine
ng-nitroarginine
nitro-l-arginine
nitroarginine
nola
omega-nitro-l-arginine
omega-nitroarginine
l-ornithin
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
N814750MACKLINNω-硝基-L-精氨酸98%30元/5g;   69元/25g;   228元/100g;   1135元/500g;   展开
储存:室温
状态:白色到灰白色粉末
N0660TCINω-Nitro-L-arginine>98.0%(T)(HPLC)190元/5G;   690元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C6H13N5O4 = 219.20
外观与形状(20℃)固体
Reaxys-RN1728914
PubChem物质ID87573972
MDL编号MFCD00007033

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Specific rotation [a]20/D+23.0 to +31.0 deg(C=2,2mol/L HCl)

物性(参考值)

比旋光度 [α]D24° (C=2,2mol/L Hcl)

相关法规

RTECS#RM2982100
280148J&KNω-Nitro-L-arginine98%86元/1G;   157元/5G;   627元/25G;   展开

基本信息

分子式C6H13N5O4
分子量219.20
熔点257
比旋光度([α]20D)+23 to +25 (C=4, 2 M HCl)
MDL编码MFCD00007033
Beilstein1728914
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK3
RTECSRM2982100
TSCA
H62061Alfa AesarNomega-Nitro-L-arginine98%947元/5g;   3491元/25g;   展开

基本信息

MDL
MFCD00007033

EINECS
218-418-9

分子式
C6H13N5O4

分子量
219.20

熔点
257°

形态
Solid

Beilstein
1728914

安全信息

RTECS
RM2982100

TSCA

N5501Sigma-AldrichNω-Nitro-L-arginine≥98% (TLC)324.21元/1 G;   770.3元/5 G;   2405.62元/25 G;   展开

产品说明

应用

Nω-硝基-L-精氨酸已被用于:

  • 作为一氧化氮合成酶 (NOS) 抑制剂,用于测量细胞色素C还原检测中一氧化氮(NO)衍生物的释放量
  • 收缩研究用纤维束的预处理
  • 作为 NOS 抑制剂表征云南红豆杉 细胞中NO的生成
  • 作为神经元一氧化氮合成酶 (nNOS) 的不可逆抑制剂对浮囊制剂作进行预先温育处理

包装

5, 25 g in poly bottle
1 g in poly tube

生化/生理作用

Nω-硝基-L-精氨酸/L-NNA 有助于降低高碳酸血症导致的皮质充血和大脑 cGMP的水平。
组成型一氧化氮合酶(nNOS)的不可逆抑制剂和诱导型一氧化氮合酶(iNOS)的可逆抑制剂。

特点和优势

《受体分类和信号转导》手册的一氧化氮合酶页面有该化合物的介绍。要浏览手册其他页,点击此处。

基本信息

经验(实验)分子式C6H13N5O4
分子量219.20
Beilstein1728914
EC 号218-418-9
MDL编号MFCD00007033
PubChem化学物质编号24278010

产品性质

质量水平200
生物来源synthetic
测定≥98% (TLC)
形式powder
mp 257 ℃
溶解性1 M HCl: 50 mg/mL, clear, colorless to faintly yellow
SMILES stringN[C@@H](CCCNC(=N)N[N+]([O-])=O)C(O)=O
InChI1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1
InChI keyMRAUNPAHJZDYCK-BYPYZUCNSA-N
Gene Informationhuman ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
mouse ... Nos2(18126)
rat ... Grin2a(24409), Nos1(24598)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
M03121FluorochemH-Arg(NO2)-OH95%220元/10g;   374元/25g;   902元/100g;   展开

基本信息

CAS Number2149-70-4
MDL NumberMFCD00007033
Melting Point257℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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