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CAS: 214360-73-3
分子式: C12H18BNO2
分子量: 219.09
熔点: 165-169℃
英文名称: 
4-Aminophenylboronic acid pinacol ester
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
2-(4-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
(4-aminophenyl)boronic acid, pinacol ester, hydrochloride
推荐供应商
货号品牌产品名称规格包装、参考价格
A801545MACKLIN4-氨基苯硼酸频哪醇酯98%26元/1g;   68元/5g;   330元/25g;   935元/100g;   咨询
储存:2~8°C
状态:白色到棕色晶体或粉末块状
T1951TCI4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline>98.0%(GC)290元/1G;   990元/5G;   咨询

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C12H18BNO2 = 219.09
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN9049485
PubChem物质ID87577652
MDL编号MFCD02093721

技术规格

AppearanceWhite to Yellow to Orange powder to crystal
Purity(GC)min. 98.0 %
Melting point166.0 to 170.0 ℃
Solubility in hot Methanolalmost transparency

物性(参考值)

熔点170 ℃
水溶性不溶

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
205857J&K4-Aminophenylboronic Acid Pinacol Ester98%248元/1G;   1009元/5G;   咨询

基本信息

分子式C12H18BNO2
分子量219.09
熔点165-169
MDL编码MFCD02093721

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA
05-1034Strem4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)anilinemin. 97%807元/1g;   3212元/5g;   咨询
H51666Alfa Aesar4-Aminobenzeneboronic acid pinacol ester98%1334元/1g;   4783元/5g;   咨询

应用
4-Aminobenzeneboronic acid pinacol ester is a reagent used for Suzuki-Miyaura cross-coupling reactions, Mercury(II) detection by fluorometry with new fluorogenic indicators based on through-bond energy transfer from pentaquinone to rhodamine, Rhodium-catalyzed amination reactions and Palladium-catalyzed Suzuki cross-coupling to synthesize potential antitubercular and antimicrobial compounds. It is also used as a reagent in preparation of Hexaphenylbenzene derivatives as a potential bioprobe and multichannel keypad system, Pyromellitic diimide-based polymer as matrix for solution-processable n-channel field-effect transistors, alternating copolymers of oligoarylenes and naphthalene bisimides as low band gap semiconductors with electrochemical and spectroelectrochemical behavior and γ-secretase modulators in the treatment of Amyloid β formation.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD02093721

分子式
C12H18BNO2

分子量
219.09

灵敏度
Ambient temperatures.

溶解性
Slightly soluble in water.

安全信息

TSCA

C36638Alfa Aesar4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline97%942元/1g;   3790元/5g;   咨询

基本信息

Ref#
36638

MDL
02093721

分子式
C12 H18 B N O2

分子量
219.09

518751Sigma-Aldrich4-Aminophenylboronic Acid Pinacol Ester97%435.28元/1 G;   1772.11元/5 G;   咨询

产品说明

应用

4-氨基苯硼酸频哪醇酯可用作反应物制备:

  • 通过与碘代色酮进行钯催化的Suzuki-Miyaura交叉偶联反应制备取代3-苯基-4H-1-苯并吡喃-4-酮。
  • 利用基于从五醌到罗丹明通过键的能量转移的荧光指示剂、通过荧光测定法检测汞(II)。
  • 铑催化的胺化反应。
  • 钯催化的Suzuki交叉偶联以合成潜在的抗结核和抗微生物化合物。

它也可用于制备:
  • 六苯基苯衍生物,作为一种潜在的生物探针和多通道键盘系统
  • 基于均苯四甲酸二酰亚胺的聚合物,作为溶液可处理的n-通道场效应晶体管的基质
  • 低聚亚芳基和萘双酰亚胺,作为低带隙半导体的替代共聚物,具有电化学和光谱电化学行为
  • γ用于治疗淀粉样蛋白β形成的分泌酶调节剂

包装

1, 5 g in glass bottle

基本信息

经验(实验)分子式C12H18BNO2
分子量219.09
MDL编号MFCD02093721
PubChem化学物质编号24874043
NACRESNA.22

产品性质

质量水平100
测定97%
mp165-169 ℃ (lit.)
SMILES stringCC1(C)OB(OC1(C)C)c2ccc(N)cc2
InChI1S/C12H18BNO2/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8H,14H2,1-4H3
InChI keyZANPJXNYBVVNSD-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
010826Fluorochem4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline99%308元/1g;   418元/5g;   1034元/25g;   咨询

基本信息

CAS Number214360-73-3
MDL NumberMFCD02093721
Boiling Point340℃
Melting Point165-172℃
Density1.05

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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