CAS 21102-95-4; 1-cyclopentanediacetimide, n-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)- d

CAS:

21102-95-4

分子式:

C₂₂H₃₁N₃O₃·₂HC

分子量:

458.42

熔点:

196.5-198.5 °C

英文名称:

1-cyclopentanediacetimide, n-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)- d

n-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimi de d

1-cyclopentanediacetimide,n-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)- dihydrochloride

用途:

BMY 7378是一种多靶点抑制剂，作用于α2C-adrenoceptor和α1D-adrenoceptor，pKi分别为6.54和8.2，且为混合型5-HT1A受体激动剂和拮抗剂，pKi为8.3。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

B863641

MACKLIN

BMY 7378 dihydrochloride

≥98%

263元/10mg;

咨询

储存：2-8°C
状态：白色固体

B794328

MACKLIN

BMY 7378 dihydrochloride

10mM in DMSO

176元/1ml;

咨询

储存：-20°C

B134

Sigma-Aldrich

BMY 7378 dihydrochloride

≥98% (HPLC), solid

3686.87元/25 MG;

咨询

产品说明

包装

25, 100 mg in poly bottle

生化/生理作用

BMY 7378 dihydrochloride is a partial 5-HT_1A serotonin receptor agonist and selective α_1D-adrenoceptor antagonist.

特点和优势

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

法律信息

Manufactured and sold with the permission of Bristol Myers Squibb Corporation.

基本信息

经验(实验)分子式	C₂₂H₃₁N₃O₃ · 2HCl
分子量	458.42
MDL编号	MFCD00153771
PubChem化学物质编号	24278080
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	solid
颜色	white
溶解性	H₂O: >5 mg/mL
SMILES string	Cl.Cl.COc1ccccc1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O
InChI	1S/C22H31N3O3.2ClH/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22;;/h2-3,6-7H,4-5,8-17H2,1H3;2*1H
InChI key	NIBOMXUDFLRHRV-UHFFFAOYSA-N
Gene Information	human ... ADRA1D(146), HTR1A(3350)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)