基本信息

技术规格

物性(参考值)

Technical Notes:

1. Biaryl bisphos phine ligand with narrow dihedral angle. The SEGPHOS® ligand has been applied to a variety of metal catalyzed reactions. In many cases, yields and enantios electivities, exceed results obtained earlier using BINAP

2.As ruthenium complex, SEGPHC S® generally gives higher levels of chiral induction in as ymmetric hydrogenations of a,ß,and y-functionalized ketones. See ruthenium complexes 44-0096, 44-0518, 44-01 68

3.Used in Rh-catalyzed transformations such as: (a) 1,4-addition of boronic acids to coumarins, (b) addition of titanium reagents to imines,' (c) cotrimerization of alkenes and acetylenes,o (d) double 2+2+2 cycloaddition," (e) indanone formation.a,

4.Used in Pd-catalyzed transformations such as: (a) cycloaddition of 1,6-enyne, (b) arylative cyclization of allenyl aldehydes with boronic acids,13 (c) synthesis of chromans.

5.Used in Cu-catalyzed transformations such as: (a) nitroso Diels-Alder,' (b) reductive aldol

6.condensation, (c) conjugate reduction of unsaturated sulfones, and phophonates

7.Iridium-catalyzed asymmetric hydrogenation of quinolines activated by chloroformates

8.Iridium-catalyzed asymmetric transfer hydrog enation used in polyketide construction.

9.Rhodium-catalyzed asymmetric hydroarylation of 3-pyrrolines.

10.P alladium-catalyzed regio- and enantioselective dearomatization of pyrroles to 2H-pyrroles.' Rhodium-catalyzed as ymmetric synthesis of cyclopentanols.0

11. Silver-catalyzed as ymmetric Mannich-type reac tion.

产品说明

应用

用于不对称反应的Takasago配体和复合物
手性联芳基双膦催化配体用于：

• 铑催化的1,3-二羰基化合物与1,6-二炔或1,6-烯炔的不对称形式烯化或环加合反应
• 通过铱催化的烯丙基乙酸酯与醇或醛的立体选择性转移氢化反应进行高烯丙基醇的立体选择性制备
• 铑催化 [2 + 2 + 2] 环加成反应合成芳基萘的轴向手性衍生物萘丙酸衍生物
• α 的非对映和对映选择性加氢-氨基-β-铱配合物催化的酮酯盐酸盐
• 镍催化脱氮制备二氢异喹啉酮苯并三嗪酮与 1,3-二烯和烯烃的环合反应
• Rh 催化炔醛立体选择性环化合成茚醇衍生物

包装

50, 100 mg in amber glass bottle

法律信息

与 Takasago 合作销售，仅用于研究目的。日本注册号 3148136
SEGPHOS is a registered trademark of Takasago Intl. Corp.

基本信息

产品性质

安全信息