| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| E794695 | MACKLIN | Entinostat (MS-275) | 10mM in DMSO | 285元/1ml; | 展开 |
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| E1454 | TCI | Entinostat | >97.0%(HPLC) | 1290元/100MG; | 展开 |
基本信息 | 纯度/分析方法 | >97.0%(HPLC) | | 分子式/分子量 | C21H20N4O3 = 376.42 | | 外观与形状(20℃) | 固体 | | 储存温度 | -20℃ | | 储存在惰性气体下 | 存放于惰性气体之中 | | 应避免的情况 | 空气,加热 | | Reaxys-RN | 8442710 | | MDL编号 | MFCD08272435 |
技术规格 | Appearance | White to Light yellow powder to crystal | | Purity(HPLC) | min. 97.0 area% | | Melting point | 157.0 to 161.0 ℃ | | NMR | confirm to structure |
物性(参考值) 安全信息 | 图形或危害标志 |   | | 信号词 | 危险 | | 危险性说明 | H301 : 吞咽会中毒。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H360 : 可能对生育能力或胎儿造成伤害。
| | 防范说明 | P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P308 + P313 : 如接触到或有疑虑：求医/就诊。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P310 + P330 : 如误吞咽：立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。
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相关法规 运输信息 | UN编号 | UN2811 | | 类别 | 6.1 | | 包装类别 | III | | 监管条件代码(*) | |
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| 625238 | J&K | Entinostat | 99% | 742元/25MG; 1347元/50MG; 2445元/100MG; | 展开 |
基本信息 | 分子式 | C21H20N4O3 | | 分子量 | 376.41 | | MDL编码 | MFCD03453552 | | 存储条件 | Freezer -20℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Danger | | 危险说明 | H301
H315
H319
H335
H360 | | 防范说明 | P201
P261
P301+P310
P305+P351+P338
P308+P313 | | UN号码 | 2811 | | 危险分类 | 6.1 | | 包装等级 | III | | WGK | 3 |
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| C46687 | Alfa Aesar | Entinostat | | 5644元/250mg; 21413元/1g; | 展开 |
基本信息 Ref#
46687 分子式
C21H20N4O3 分子量
391.55 GHS危害和防范说明 Hazard Statements
H301 H315 H319 H335 H360 Precautionary Statements
P301+P330+P331 P302+P352 P305+P351+P338 P304+P340 P312 P280 安全信息 危险等级
6.1 |
| EPS002 | Sigma-Aldrich | MS-275 | A HDAC1 and HDAC3 inhibitor | 17004.3元/5 MG; | 展开 |
产品说明 一般描述 优先于HDAC3(IC50=8 μM)抑制HDAC1(IC50 = 300nM)。 对HDAC8(IC50>100 μM)无抑制活性。 应用 MS-275已被用作组蛋白脱乙酰酶-1抑制剂。 生化/生理作用 HDAC抑制剂，抗增殖。 基本信息 | 经验(实验)分子式 | C21H20N4O3 | | 分子量 | 376.41 | | MDL编号 | MFCD03453552 | | PubChem化学物质编号 | 329799578 | | NACRES | NA.41 |
产品性质 | 质量水平 | 100 | | 测定 | ≥99% | | 溶解性 | DMSO: 38 mg/mL | | 储存温度 | −20℃ | | SMILES string | Nc1ccccc1NC(=O)c2ccc(CNC(=O)OCc3cccnc3)cc2 | | InChI | 1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26) | | InChI key | INVTYAOGFAGBOE-UHFFFAOYSA-N | | Gene Information | human ... HDAC1(3065), HDAC10(83933), HDAC11(79885), HDAC2(3066), HDAC3(8841), HDAC4(9759), HDAC5(10014), HDAC6(10013), HDAC7(51564), HDAC8(55869), HDAC9(9734) |
安全信息 | 象形图 | | | 警示用语： | Danger | | 危险声明 | H301 - H360 | | 预防措施声明 | P201 - P301 + P310 + P330 | | 危险分类 | Acute Tox. 3 Oral - Repr. 1A | | 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 050699 | Fluorochem | Entinostat, Free Base | >99% | 2794元/250mg; 6842元/1g; | 展开 |
基本信息 | CAS Number | 209783-80-2 | | MDL Number | MFCD08272435 | | Melting Point | 159-160℃ | | Density | 1.315 |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H360: May damage fertility or the unborn child ..
| | 防范说明 | P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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