CAS 209589-59-3; n<sup>δ</sup>-(s-methyl)isothioureido-l-ornithine; s-methyl-l-thiocitrulline, dihydrochloride-cas 209589-59-3-calbiochem

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CAS:

209589-59-3

分子式:

C₇H₁₅N₃O₂S • ₂HCl

分子量:

278.2

中文名称:

n^δ-(s-methyl)isothioureido-l-ornithine

n ^δ-(s-methyl)isothioureido-l-ornithine

英文名称:

s-methyl-l-thiocitrulline, dihydrochloride-cas 209589-59-3-calbiochem

用途:

S-methyl-L-Thiocitrulline hydrochloride is a potent NOS inhibitor with selectivity toward the neuronal isoform compared to eNOS and iNOS.

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货号

品牌

产品名称

规格

包装、参考价格

S912101

MACKLIN

S-methyl-L-Thiocitrulline hydrochloride

98%

3583元/20mg;

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储存：-20°C，密闭，干燥

472804

Millipore

S-Methyl-L-thiocitrulline, Dihydrochloride-CAS 209589-59-3-Calbiochem

A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzym

2724.16元/10 MG;

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产品说明

一般描述

A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.4 µM).
A cell-permeable, inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.4 µM).

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
Rat neuronal nitric oxide synthase
Product does not compete with ATP.
Reversible: no
Target IC₅₀: 300 nM for rat neuronal nitric oxide synthase

警告

Toxicity: Standard Handling (A)

其他说明

Krishnaswamy, N., et al. 1995. J. Biol. Chem.270, 11103.
Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem.37, 885.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₇H₁₅N₃O₂S · 2HCl
分子量	278.20

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated (hygroscopic)
颜色	white to off-white
溶解性	water: 50 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1
InChI key	NGVMVBQRKZPFLB-YFKPBYRVSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3

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