CAS 209394-46-7; ladostigil tartrate

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CAS:

209394-46-7

分子式:

C₂₀H₂₆N₂O₈

分子量:

694.77

英文名称:

ladostigil tartrate

(3R)-(n-propargylaminoindan-5-yl)-ethyl methyl carbamate tartrate (2:1)

tv-3326

tv3326

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

L933783

MACKLIN

Ladostigil hemitartrate

4600元/10mg;

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储存：2-8°C，干燥，密封

SML2263

Sigma-Aldrich

Ladostigil tartrate

≥98% (HPLC)

827.34元/5 MG; 3336.73元/25 MG;

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产品说明

生化/生理作用

Ladostigil, a carbamate is also a butyryl cholinesterase (BuChE) inhibitor. It possesses anti-inflammatory property and effectively reduces the levels of tumor necrosis factor α (TNF-α) in lipopolysaccharide (LPS)-activated macrophages. It provides protection to cardiomyocytes. Ladostigil has neuroprotective functionality and has the potential to treat mild cognitive impairment (MCI) and spatial memory deficits development. It also exhibits protective effects during oxidative and nitrative stress.
Multifunctional drug designed to treat Alzhemier′s disease by combining in a single molecule the neuroprotective/neurorestorative effects of the (MAO)-B inhibitor rasagiline with the cholinesterase (ChE) inhibitory activity of rivastigmine.

基本信息

经验(实验)分子式	C₁₆H₂₀N₂O₂ · 0.5C₄H₆O₆
分子量	347.39
MDL编号	MFCD22741393

产品性质

测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 2 mg/mL, clear
储存温度	2-8℃
InChI	1S/2C16H20N2O2.C4H6O6/c21-4-10-17-15-9-7-12-6-8-13(11-14(12)15)20-16(19)18(3)5-2;5-1(3(7)8)2(6)4(9)10/h21,6,8,11,15,17H,5,7,9-10H2,2-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t2*15-;1-,2-/m111/s1
InChI key	PRLVBVAJMQZMJN-OGOSNNLPSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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