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CAS: 2089-82-9
分子式: C16H10N2O
分子量: 246.26
英文名称: 
sajm589
5-hydroxybenzo[a]phenazine
benzo[a]phenazin-5-ol
推荐供应商
货号品牌产品名称规格包装、参考价格
A937925MACKLINBenzo[a]phenazin-5-ol≥99%1320元/5mg;   2091元/10mg;   咨询
储存:2-8°C,密封,干燥
状态:固体
SML2198Sigma-AldrichsAJM589≥98% (HPLC)1311.9元/5 MG;   4232.97元/25 MG;   咨询

产品说明

生化/生理作用

sAJM589 is a Myc inhibitor that disrupts the Myc-Max heterodimer with an IC50 value of 1.8 μM. sAJM589 was shown to suppress cellular proliferation in a variety of MYC-dependent cancer cell line including strong inhibition of Burkitt lymphoma Raji cell line growth. The mechanism of action of sAJM589 is thought to involve increased ubiquitination of Myc by inhibition of Max binding to Myc, leading to proteasome-mediated degradation.

基本信息

经验(实验)分子式C16H10N2O
分子量246.26
MDL编号MFCD00437759
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色 yellow to orange
溶解性DMSO: 2 mg/mL, clear (warmed)
储存温度−20℃
SMILES stringOC1=C2C(C=CC=C2)=C3C(N=C(C=CC=C4)C4=N3)=C1

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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