CAS 208445-06-1; rp-8-bromoguanosine- 3′, 5′- cyclic monophosphorothioate sodium salt; rp-8-br-cgmps sodium salt

CAS:

208445-06-1

分子式:

C₁₀H₁₀BrN₅NaO₆PS

分子量:

462.1

中文名称:

rp-8-bromoguanosine- 3′, 5′- cyclic monophosphorothioate sodium salt

英文名称:

rp-8-br-cgmps sodium salt

rp-8-bromo-cgmps sodium salt

用途:

Rp-8-bromo-Cyclic GMPS sodium salt is a cell-permeable cGMP analog that adds an equatorial exocyclic (Rp) sulfur substitution in the axial position of the cyclophosphate ring of 8-bromo-cGMP.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

R912083

MACKLIN

Rp-8-bromo-Cyclic GMPS sodium salt

98%

5182元/1mg;

咨询

储存：-20°C，密闭，干燥

SML1614

Sigma-Aldrich

Rp-8-Br-cGMPS sodium salt

≥98% (HPLC)

4094.18元/1 MG; 13242.5元/5 MG;

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产品说明

生化/生理作用

Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition.

基本信息

经验(实验)分子式	C₁₀H₁₀BrN₅O₆PS · Na
分子量	462.15
MDL编号	MFCD04037242
PubChem化学物质编号	329825500
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	lyophilized solid
颜色	white to beige
储存温度	−20℃
SMILES string	O=C1C2=C(N([C@@H]3O[C@H](CO[P@@](O4)([O-])=S)[C@@H]4[C@H]3O)C(Br)=N2)N=C(N)N1.[Na+]
InChI	1S/C10H11BrN5O6PS.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(21-8)1-20-23(19,24)22-5;/h2,4-5,8,17H,1H2,(H,19,24)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-,23-;/m1./s1
InChI key	CHTSSROWUAICIL-GMKUFTCMSA-M

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable