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关键词:       仅模糊查询
CAS: 2078-54-8
分子式: C12H18O
分子量: 178.27
沸点: 256℃(764
熔点: 18℃
中文名称: 
2,6-二异丙基酚
2,6-双(1-甲基乙基)苯酚
2,6-二异丙基苯酚
丙泊酚
2,6-双(1-甲乙基)苯酚
英文名称: 
2,6-Diisopropyl phenol
2,6-bis(1-methylethyl)-Phenol
2,6-diisopropyl-pheno
2,6-bis(1-methylethyl)phenol
2,6-diisopropylphenol
diprivan
disoprofol
ici 35868
2,6-bis(1-methylethyl)-pheno
propofol
2,6-Bis(Isopropyl)-phenol
2,6-diisopropyl-phenol
Phenol,2,6-bis(1-methylethyl)-
Phenol,2,6-diisopropyl-
2,6-Bis(isopropyl)phenol
Diprivan 10
PD 18215
propofol(INN)
2,6-di(1-methylethyl)phenol
展开更多英文名
性质描述: 该品熔点18℃，沸点256℃，136℃（4.0kPa），126℃（2.27kPa），相对密度0.962（20/4℃），折光率1.5140。
生产方法: 由丙烯与苯酚经烷基化而得。在强烈搅拌并充入氮气的情况下，将4.5g铝屑加入565g预热到165℃的苯酚中，待放出氢气后即可停止反应。将此反应混合物装入高压釜内，通入丙烯，在240℃反应2h。在反应过程中将压力从1.37MPa渐渐增加到3.43MPa。反应毕，冷却，将釜内物料加至200ml5%的盐酸中，震荡。将混合物过滤，水洗。加甲苯通过恒沸蒸馏干燥产物，再经分馏得到656g产品，收率61%。
用途: 该品是一种麻醉剂，也是麝香DDHI的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D0617TCI2,6-Diisopropylphenol>98.0%(GC)340元/25G;   3140元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C12H18O = 178.28
外观与形状(20℃)液体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN1866484
PubChem物质ID87567266
SDBS (AIST Spectral DB)862
Merck Index (14)7834
MDL编号MFCD00008885

技术规格

AppearanceColorless to Red to Green clear liquid
Purity(GC)min. 98.0 %

物性(参考值)

熔点18 ℃
沸点242 ℃
闪点113 ℃
比重0.96
折射率1.51

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H410 : 对水生生物毒性极大并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P391 : 收集溢出物。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。

相关法规

RTECS#SL0810000

运输信息

UN编号UN3082
类别9
包装类别 III
监管条件代码(*)
L06841Alfa Aesar2,6-Diisopropylphenol97%384元/25g;   2370元/100g;   6413元/500g;   展开

应用
2,6-Diisopropylphenol plays the role of an antioxidant by reacting with free radicals to form a phenoxyl radical, a property associated with all phenol-based free radical scavengers. It is an effective intravenous hypnotic agent, widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. It is useful for the induction and maintenance of general anaesthesia.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00008885

EINECS
218-206-6

分子式
C12H18O

分子量
178.28

熔点
17-18°

沸点
254-256°

闪点
113°(235°F)

密度
0.962

折射率
1.5140

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Very slightly soluble in water.

Beilstein
1866484

Merck
14,7834

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

UN#
UN3145

危险等级
8

包装组
III

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
23-26-36/37-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
SL0810000

TSCA
是

PHR1663SupelcoPropofolPharmaceutical Secondary Standard; Certified Reference Material2370.89元/1 ML;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propofol is approved for induction and maintenance of paediatric anesthesia and sedation in children less than 3 years of age. The mechanism of action involves interaction with gamma-aminobutyric acid A receptor. Rapid effect and fewer side effects like postoperative nausea makes propofol a popular intravenous anesthetic agents.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Propofol may be used as a pharmaceutical reference standard for the determination of the analyte in emulsion dosage form by sequential injection technique with spectrophotometric and fluorimetric detections.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA5999 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式[(CH3)2CH]2C6H3OH
分子量178.27
EC 号218-206-6
MDL编号MFCD00008885
PubChem化学物质编号329823540
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
蒸汽压5.6 mmHg ( 100 ℃)
CofAcurrent certificate can be downloaded
包装ampule of 1 mL
technique(s)HPLC: suitable
gas chromatography (GC): suitable
折射率n20/D 1.514 (lit.)
bp256 ℃/764 mmHg (lit.)
mp18 ℃ (lit.)
密度0.962 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 1031
traceable to PhEur Y0000016
traceable to USP 1572503
储存温度2-8℃
SMILES stringCC(C)c1cccc(C(C)C)c1O
InChI1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI keyOLBCVFGFOZPWHH-UHFFFAOYSA-N
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
Y0000016PropofolEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 650 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式[(CH3)2CH]2C6H3OH
分子量178.27
MDL编号MFCD00008885
PubChem化学物质编号329830815
NACRESNA.24

产品性质

等级pharmaceutical primary standard
蒸汽压5.6 mmHg ( 100 ℃)
manufacturer/tradenameEDQM
折射率n20/D 1.514 (lit.)
bp256 ℃/764 mmHg (lit.)
mp18 ℃ (lit.)
密度0.962 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCC(C)c1cccc(C(C)C)c1O
InChI1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI keyOLBCVFGFOZPWHH-UHFFFAOYSA-N
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
Y0000017Propofol for peak identificationEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 0.1 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式[(CH3)2CH]2C6H3OH
分子量178.27
MDL编号MFCD00008885
PubChem化学物质编号329830816
NACRESNA.24

产品性质

等级pharmaceutical primary standard
蒸汽压5.6 mmHg ( 100 ℃)
manufacturer/tradenameEDQM
折射率n20/D 1.514 (lit.)
bp256 ℃/764 mmHg (lit.)
mp18 ℃ (lit.)
密度0.962 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCC(C)c1cccc(C(C)C)c1O
InChI1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI keyOLBCVFGFOZPWHH-UHFFFAOYSA-N
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
D126608Sigma-Aldrich2,6-Diisopropylphenol97%431.63元/5 G;   1701.97元/100 G;   展开

产品说明

一般描述

2,6-二异丙基苯酚(一种强疏水取代苯酚)是一种新型静脉麻醉剂。已研究 2,6-二异丙基苯酚(异丙酚)的抗氧化属性。2,6-二异丙基苯酚是一种有效的静脉注射催眠药，广泛用于麻醉诱导和维持以及重症监护病房的镇静。用于全身麻醉的诱导和维持。

应用

2,6-二异丙基苯酚是研究其对离体大鼠肝线粒体氧化磷酸化作用的合适试剂。是制备双(2,6-二异丙基苯氧基)双(2-甲基-8-喹啉)钛 (IV) 配合物的合适试剂。

包装

5, 100 g in glass bottle

基本信息

线性分子式[(CH3)2CH]2C6H3OH
分子量178.27
EC 号218-206-6
MDL编号MFCD00008885
PubChem化学物质编号24278001
NACRESNA.22

产品性质

蒸汽压5.6 mmHg ( 100 ℃)
质量水平100
测定97%
折射率n20/D 1.514 (lit.)
bp256 ℃/764 mmHg (lit.)
mp18 ℃ (lit.)
密度0.962 g/mL at 25 ℃ (lit.)
SMILES stringCC(C)c1cccc(C(C)C)c1O
InChI1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI keyOLBCVFGFOZPWHH-UHFFFAOYSA-N
Gene Informationhuman ... CYP1A2(1544), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)
rat ... Gabra2(29706)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
BP1031PropofolBritish Pharmacopoeia (BP) Reference Standard2244.51元/1 ML;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 1 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

线性分子式[(CH3)2CH]2C6H3OH
分子量178.27
EC 号218-206-6
MDL编号MFCD00008885
NACRESNA.24

产品性质

等级pharmaceutical primary standard
蒸汽压5.6 mmHg ( 100 ℃)
manufacturer/tradenameBP
折射率n20/D 1.514 (lit.)
bp256 ℃/764 mmHg (lit.)
mp18 ℃ (lit.)
密度0.962 g/mL at 25 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringCC(C)c1cccc(C(C)C)c1O
InChI1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI keyOLBCVFGFOZPWHH-UHFFFAOYSA-N
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
1572503USPPropofolUnited States Pharmacopeia (USP) Reference Standard3231.47元/500 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式[(CH3)2CH]2C6H3OH
分子量178.27
MDL编号MFCD00008885
PubChem化学物质编号329750986
NACRESNA.24

产品性质

等级pharmaceutical primary standard
蒸汽压5.6 mmHg ( 100 ℃)
manufacturer/tradenameUSP
折射率n20/D 1.514 (lit.)
bp256 ℃/764 mmHg (lit.)
mp18 ℃ (lit.)
密度0.962 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCC(C)c1cccc(C(C)C)c1O
InChI1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI keyOLBCVFGFOZPWHH-UHFFFAOYSA-N
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9