CAS 20724-73-6; 2'-c-甲基胞嘧啶核苷; nm107

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CAS:

20724-73-6

分子式:

C₁₀H₁₅N₃O₅

分子量:

257.24

中文名称:

2'-c-甲基胞嘧啶核苷

2′-c-methylcytidine

2′-c-methyl cytidine

英文名称:

nm107

用途:

NM107 (2'-C-Methylcytidine) 是丙型肝炎病毒 (HCV) NS5B 聚合酶的核苷抑制剂，其在野生型复制子细胞中的 EC50 为 1.85 μM。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

N880605

MACKLIN

NM107

≥99%

471元/100mg; 772元/250mg; 2204元/1g; 7751元/5g;

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储存：2-8℃
状态：白色到灰白色固体

M4949

Sigma-Aldrich

2′-C-Methylcytidine

≥95% (HPLC), powder

1156.56元/5 MG; 4439.57元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.

基本信息

经验(实验)分子式	C₁₀H₁₅N₃O₅
分子量	257.24
MDL编号	MFCD02682947
PubChem化学物质编号	329817997
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to off-white
溶解性	H₂O: >20 mg/mL
储存温度	−20℃
SMILES string	C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1N2C=CC(N)=NC2=O
InChI	1S/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1
InChI key	PPUDLEUZKVJXSZ-VPCXQMTMSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

226516

Fluorochem

2'-C-Methylcytidine

95%

1826元/250mg; 5170元/1g; 17754元/5g;

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基本信息

CAS Number	20724-73-6
MDL Number	MFCD02682947
Melting Point	230-250℃

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .

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