CAS 20357-25-9; 6-硝基藜芦醛; 4,5-Dimethoxy-6-nitrobenzaldehyde

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产品名称

规格

包装、参考价格

详情

N795507

MACKLIN

6-硝基黎芦醛

10mM in DMSO

308元/1ml;

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储存：-20°C

N842858

MACKLIN

6-硝基黎芦醛

97%

27元/1g; 39元/5g; 162元/25g; 637元/100g; 3184元/500g;

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储存：2-8°C,惰性气体氛围
状态：白色到黄色固体

N0538

TCI

6-Nitroveratraldehyde

>85.0%(GC)

285元/5G; 1200元/25G;

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基本信息

纯度/分析方法	>85.0%(GC)
分子式/分子量	C₉H₉NO₅ = 211.17
外观与形状(20℃)	固体
储存在惰性气体下	存放于惰性气体之中
应避免的情况	光,空气
Reaxys-RN	395599
PubChem物质ID	87573861
MDL编号	MFCD00007134

技术规格

Appearance	White to Light yellow to Green powder to crystal
Purity(GC)	min. 85.0 %
Melting point	132.0 to 136.0 ℃

物性(参考值)

熔点

132 ℃

328103

J&K

4,5-Dimethoxy-2-nitrobenzaldehyde

85%

162元/5G; 476元/25G;

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基本信息

分子式	C₉H₉NO₅
分子量	211.17
熔点	128-135
MDL编码	MFCD00007134
Beilstein	395599
EINECS 编号	243-762-1

安全信息

防范说明	P262
WGK	3
TSCA	否

A14415

Alfa Aesar

6-Nitroveratraldehyde

96%

665元/5g; 986元/10g; 2210元/25g;

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应用
6-Nitroveratraldehyde has been used in the preparation of no-carrier-added 6-18F-fluoro-L-dopa, fundamental tracer for cerebral positron emission tomography studies of dopaminergic system in humans and o-nitroaryl-bis(5-methylfur-2-yl)methanes, versatile synthons for the synthesis of nitrogen-containing heterocycles. DMNB is also an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair. It is also used for synthesizing analogs of alpha-asarone.

备注
Air and light sensitive. Store away from air, light and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

基本信息

MDL
MFCD00007134

EINECS
243-762-1

分子式
C₉H₉NO₅

分子量
211.17

熔点
131-135°

灵敏度
Air Sensitive. Light Sensitive. Ambient temperatures.

形态
Powder

溶解性
Insoluble in water. Soluble to 25 mM in ethanol with gentle warming and to 100 mM in DMSO.

Beilstein
395599

安全信息

TSCA
否

279609

Sigma-Aldrich

6-Nitroveratraldehyde

technical grade, 80%

440.06元/5 G; 1541.55元/25 G;

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产品说明

应用

6-Nitroveratraldehyde has been used in the preparation of:

no-carrier-added 6-¹⁸F-fluoro-L-dopa, fundamental tracer for cerebral positron emission tomography studies of dopaminergic system in humans
o-nitroaryl-bis(5-methylfur-2-yl)methanes, versatile synthons for the synthesis of nitrogen-containing heterocycles

包装

5, 25 g in poly bottle

基本信息

线性分子式	O₂NC₆H₂-3,4-(OCH₃)₂CHO
分子量	211.17
EC 号	243-762-1
MDL编号	MFCD00007134
PubChem化学物质编号	24856896
NACRES	NA.22

产品性质

等级	technical grade
质量水平	100
测定	80%
mp	131-133 ℃ (lit.)
SMILES string	COc1cc(C=O)c(cc1OC)[N+]([O-])=O
InChI	1S/C9H9NO5/c1-14-8-3-6(5-11)7(10(12)13)4-9(8)15-2/h3-5H,1-2H3
InChI key	YWSPWKXREVSQCA-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

260960

Sigma-Aldrich

DNA-PK Inhibitor-CAS 20357-25-9-Calbiochem

The DNA-PK Inhibitor, also referenced under CAS 20357-25-9, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appl

1709.38元/10 MG;

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产品说明

一般描述

A cell-permeable vanillin derivative that acts as a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK) activity (IC₅₀ = 15 µM) and DNA-PK-mediated double strand break (DSB) DNA repair by non-homologous DNA-end-joining (NHEJ). Reported to effectively sensitize cells to Cisplatin (Cat. No. 232120). Does not affect the activities of PKC or Chk2.
A cell-permeable vanillin derivative that acts as a potent and selective inhibitor of DNA-PK (DNA-dependent protein kinase) activity (IC₅₀ = 15 µM) and DNA-PK-mediated DSB (double strand break) DNA repair by NHEJ (non-homologous DNA-end-joining). Shown to effectively sensitize cells to killing by Cisplatin (Cat. No. 232120). Does not affect PKC or Chk2 kinase activities.

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
DNA-PK activity
Product does not compete with ATP.
Reversible: no
Target IC₅₀: 15 µM against DNA-PK (DNA-dependent protein kinase) activity

警告

Toxicity: Carcinogenic / Teratogenic (D)

重悬

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Willmore, E., et al. 2004. Blood,103, 4659.
Durant, S., and Karran, P. 2003. Nucleic Acids Res.31, 5501.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₉H₉NO₅
分子量	211.17
MDL编号	MFCD00007134

产品性质

质量水平	100
测定	≥90% (GC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	bright yellow
溶解性	DMSO: 5 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C9H9NO5/c1-14-8-3-6(5-11)7(10(12)13)4-9(8)15-2/h3-5H,1-2H3
InChI key	YWSPWKXREVSQCA-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable