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CAS: 2032-35-1
分子式: C6H13BrO2
分子量: 197.07
沸点: 66-67℃(1
中文名称: 
溴乙醛缩二乙醇
β-溴代乙醛缩二乙醇
1,1-二乙氧基-2-溴乙烷
溴乙缩醛
2-溴-1,1-二乙氧基乙烷
溴化阿西酞
溴代乙缩醛
溴乙醛二乙基乙缩醛
溴代乙醛缩二乙醇
英文名称: 
bromoacetaldehyde dlethyl acetal
2-bromo-1,1-diethoxy-Ethane
2-bromo-1,1-diethoxy-ethan
bromoacetaldehyde diethyl acetal
-Bromodiethyl acetal
2-Bromo-1,1-diethoxyethane
Brom acetal
2,2-Diethoxyethyl Bromide
Ethane,2-bromo-1,1-diethoxy-
2-bromo-1,1-diethoxy-ethane
性质描述: 液体。沸点180℃[170℃(分解)],相对密度1.280(20/4℃),折射率1.4376(1.4418),闪点51℃。溶于乙醇和乙醚。
生产方法: 由乙酸乙烯酯经溴化、醇解而得:将乙酸乙烯酯、无水乙醇混匀冷却至-10℃,在搅拌下缓慢滴加溴素,保持-5℃,加毕。再逐渐升温至60℃维持1h后,冷却至10℃,加入1倍量的冰水,再用氨水中和至pH=6,静置分层,油层用一倍量冰水洗涤一次,分出油层,减压分馏。收集71-76℃(2.67kPa),馏分,即为成品。工业品含量≥96.5%。原料消耗定额:乙酸乙烯酯769kg/t、无水乙醇2154kg/t、溴素1338kg/t。
用途: 医药中间体。用于制甲状腺亢进药甲硫咪唑、甲亢平及扑尔敏等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
B802416MACKLIN溴乙醛缩二乙醇93%32元/25g;   62元/100g;   展开
储存:2~8°C
状态:无色到浅黄色液体
折射率:n20/D 1.439(lit.)
B821339MACKLIN溴乙醛缩二乙醇97%41元/25g;   108元/100g;   296元/500g;   493元/1kg;   1951元/5kg;   展开
储存:2~8°C
状态:无色到黄色液体
折射率:n20/D 1.439(lit.)
B0957TCIBromoacetaldehyde Diethyl Acetal>95.0%(GC)185元/25ML;   385元/100ML;   1285元/500ML;   展开

基本信息

纯度/分析方法>95.0%(GC)
分子式/分子量C6H13BrO2 = 197.07
外观与形状(20℃)液体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (分解)
Reaxys-RN635754
PubChem物质ID87563916
SDBS (AIST Spectral DB)3351
MDL编号MFCD00000214

技术规格

AppearanceColorless to Light yellow clear liquid
Purity(GC)min. 95.0 %

物性(参考值)

沸点67 ℃/18 mmHg
闪点51 ℃
比重1.28
折射率1.44

安全信息

图形或危害标志
信号词危险
危险性说明H301 + H331 : 吞咽或吸入可致中毒。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H226 : 易燃液体和蒸气。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P240 : 容器和装载设备接地/等势联接。
P210 : 远离热源/火花/明火/热表面。禁止吸烟。
P233 : 保持容器密闭。
P243 : 采取防止静电放电的措施。
P241 : 使用防爆的电气/通风/照明设备。
P242 : 只能使用不产生火花的工具。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P370 + P378 : 火灾时:使用干砂、干粉或抗醇泡沫灭火。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P304 + P340 + P311 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P403 + P235 : 存放在通风良好的地方。保持低温。
P405 : 存放处须加锁。

运输信息

UN编号UN1992
类别3 / 6.1
包装类别 III
监管条件代码(*)
540180J&KBromoacetaldehyde Diethyl Acetal97%183元/100G;   546元/500G;   展开

基本信息

分子式C6H13BrO2
分子量197.07
沸点66-67
闪点51
密度1.31
折光率(n20D)1.4380 - 1.4400
MDL编码MFCD00000214
Beilstein635754
EINECS 编号217-989-1
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H301
H315
H319
H330
防范说明P260
P284
P301+P310
P305+P351+P338
P310
UN号码2810
危险分类6.1
包装等级II
WGK3
TSCA
A13276Alfa AesarBromoacetaldehyde Diethyl Acetal97%636元/100g;   1660元/500g;   8085元/2500g;   展开

应用
Bromoacetaldehyde diethyl acetal, is used as a synthetic building block. It is mainly used for synthesis of antibiotics such as erythromycin and cephalosporins and to other drugs. It also can be used as pharmaceutical intermediates. Besides, this chemical can be used to pruduce drugs such as methylthio imidazole, chlorpheniramine and others for thyroid. It also acts as a Useful intermediate for the preparation of other ?-heterosubstituted acetaldehyde acetals.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 - 8?°C. Protect from frost, heat and sunlight. Stable under recommended storage conditions. Keep away from Strong oxidizing agents, Acids. Moisture Sensitive.

基本信息

MDL
MFCD00000214

EINECS
217-989-1

分子式
C6H13BrO2

分子量
197.08

沸点
66-67°/18mm

闪点
61°(142°F)

密度
1.270

折射率
1.4390

灵敏度
Keep Cold. Moisture Sensitive.

形态
Liquid

溶解性
It is immiscible with water.

Beilstein
635754

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H301-H330-H315-H319-H335
Combustible liquid.Toxic if swallowed.Fatal if inhaled.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P301+P310a-P304+P340-P305+P351+P338-P320-P330-P405-P501a
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment is urgent (see label).Rinse mouth.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
II

危险类别
22-23-36/37/38
Harmful if swallowed.Toxic by inhalation.Irritating to eyes, respiratory system and skin.

安全等级
4-9-20-23-26-36/37/39-45-60
Keep away from living quarters.Keep container in a well-ventilated place.When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

TSCA

123986Sigma-AldrichBromoacetaldehyde Diethyl Acetal97%345.98元/100 G;   1614.23元/500 G;   1650.48元/1 KG;   展开

产品说明

一般描述

溴乙醛二乙基缩醛与无水三甲胺反应生成甘氨酸甜菜碱醛。在 KOH/Cu 存在下与不同的硫酚反应生成相应的酮和二乙基缩醛。
可能会在存储期间变黑。

应用

溴乙醛二乙基缩醛已用于合成单体 2-(2,2-二甲氧基)乙氧基乙烯基醚。它已被用作合成砌块。

包装

100, 500 g in glass bottle
1 kg in glass bottle

基本信息

线性分子式BrCH2CH(OC2H5)2
分子量197.07
Beilstein635754
EC 号217-989-1
MDL编号MFCD00000214
PubChem化学物质编号24847591
NACRESNA.22

产品性质

测定97%
形式liquid
折射率n20/D 1.439 (lit.)
bp66-67 ℃/18 mmHg (lit.)
密度1.31 g/mL at 25 ℃ (lit.)
储存温度2-8℃
SMILES stringCCOC(CBr)OCC
InChI1S/C6H13BrO2/c1-3-8-6(5-7)9-4-2/h6H,3-5H2,1-2H3
InChI keyLILXDMFJXYAKMK-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H319 - H330
预防措施声明P301 + P310 + P330 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
危险分类Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)149.0 °F - closed cup
闪点(C)65 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
963646AmethystBromoacetaldehyde Diethyl Acetal97%, 用于合成58元/25G;   113元/100G;   415元/500G;   1655元/2.5KG;   展开

基本信息

分子式C6H13BrO2
分子量197.07
沸点66-67
闪点51
密度1.31
折光率(n20D)1.5980 - 1.6000
MDL编码MFCD00000214
Beilstein635754
EINECS 编号217-989-1
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H301
H315
H319
H330
防范说明P260
P284
P301+P310
P305+P351+P338
P310
UN号码2810
危险分类6.1
包装等级II
WGK3
TSCA
003024FluorochemBromoacetaldehyde Diethyl Acetal97%220元/1g;   308元/25g;   616元/100g;   1210元/250g;   展开

基本信息

CAS Number2032-35-1
MDL NumberMFCD00000214
Boiling Point66-67℃/18mm
Density1.31

安全信息

图形或危害标志
危险性说明 H226: Flammable liquid and vapour.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P210: Keep away from – No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof ./ equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P370 + P378: In case of fire: Use sand, CO2 or extinguishing powder for extinction.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P403 + P235: Store in a well-ventilated place. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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