CAS 20064-19-1; 丙酰-l-肉碱; propionyl-l-carnitine

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CAS:

20064-19-1

分子式:

C₁₀H₁₉NO₄

分子量:

217.26

中文名称:

丙酰-l-肉碱

(2 r )-3-羧基- n 、 n 、 n -三甲基-2-(1-氧代丙氧基)-1-丙胺内盐

l -肉碱丙酰基酯

丙酰- l -肉碱

c3-肉碱

英文名称:

propionyl-l-carnitine

propanoyl-l-carnitine

(2r)-3-carboxy-n,n,n-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt

l-carnitine propionyl ester

c3-carnitine

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

P915748

MACKLIN

丙酰-L-肉碱

94.0% (HPLC)

898元/10mg; 1299元/25mg;

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储存：2-8°C
状态：白色到灰白色粉末或晶体

42602

Sigma-Aldrich

Propionyl-L-carnitine

≥94.0% (HPLC)

773.44元/10 MG; 2207.76元/50 MG;

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产品说明

一般描述

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

应用

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

生化/生理作用

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

基本信息

经验(实验)分子式	C₁₀H₁₉NO₄
分子量	217.26
MDL编号	MFCD00870024
PubChem化学物质编号	329756246
NACRES	NA.26

产品性质

质量水平	100
测定	≥94.0% (HPLC)
形式	powder or crystals
旋光性	[α]/D -23±3°, c = 1 in H₂O
technique(s)	LC/MS: suitable
杂质	≤10% water (calcd. from elemental analysis)
颜色	white to off-white
储存温度	2-8℃
SMILES string	[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
InChI	1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChI key	UFAHZIUFPNSHSL-MRVPVSSYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

91275

Supelco

Propionyl-L-carnitine

analytical standard

1301.5元/10 MG; 4247.18元/50 MG;

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产品说明

一般描述

Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

应用

Propionyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques. It may also be used as an analytical standard in monitoring the analyte in chemical synthesis procedures and pharmaceutical formulations using a stereospecific enzyme assay and high-performance liquid chromatography technique with UV detection.

基本信息

经验(实验)分子式	C₁₀H₁₉NO₄
分子量	217.26
MDL编号	MFCD00870024
NACRES	NB.21

产品性质

等级	analytical standard
质量水平	100
测定	≥94.0% (HPLC)
旋光性	[α]/D -24.0±2.0°, c = 0.2 in H₂O
保质期	limited shelf life, expiry date on the label
杂质	≤13% water ((calculated from elemental analysis)
application(s)	clinical testing
格式	neat
储存温度	2-8℃
SMILES string	[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
InChI	1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChI key	UFAHZIUFPNSHSL-MRVPVSSYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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