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位置：首页 > 资料中心 > 化工字典 > 2001-95-8
关键词:       仅模糊查询
CAS: 2001-95-8
分子式: C36H60N4O12
分子量: 740.88
熔点: 187-191℃
中文名称: 
缬氨霉素
英文名称: 
valinomycin
1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane- 2,5,8,11,
14,17,20,23,26,29,32,35-dodecone, 12,24,36-trimetyl-3,6,9,15,18,21,27,30,33-non
antibiotic n-329 b
cyclic(d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l-valyl-d-alpha- hydroxyisov
aleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisovaleryl-d- valyl-l-lactoyl-l
nsc 122023
valinomicin
Potassium ionophore I
Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3:HyIva =α-Hydroxyisovaleric acid,Lac =Lactic acid
valinomycin1
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
V820378MACKLIN缬氨霉素≥98%(TLC),≥95%(HPLC),solid214元/5mg;   419元/10mg;   1338元/50mg;   2265元/100mg;   5579元/250mg;   展开
储存：2~8°C
状态：白色到灰白色固体,粉末,或晶体
227304J&KValinomycin97%, 来源于极暗黄链霉菌876元/10MG;   2399元/50MG;   展开

基本信息

分子式C54H90N6O18
分子量1111.33
熔点187-188
闪点87
MDL编码MFCD00005114
Beilstein78657
EINECS 编号217-896-6
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H300
H310
防范说明P264
P280
P301+P310
P302+P350
P310
UN号码2811
危险分类6.1
包装等级I
WGK3
RTECSYV9468000
V3639Sigma-AldrichValinomycinReady Made Solution, ~1 mg/mL in DMSO798.75元/5 ML;   展开

产品说明

一般描述

Chemical structure: peptide

应用

Valinomycin is a cyclic dodecadepsipeptides with potassium ionophoric properties. It is used to study ion transport in biological systems. It is used to study its inhibitory effect on intact cells and the growth of bacteria and yeast. It is used to induce apoptosis.

包装

5 mL in glass bottle

生化/生理作用

Valinomycin is a K+-selective ionophoric cyclodepsipeptide. It is a potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction. It is reported to be insecticidal, nematicidal and antiviral.
K+选择性离子载体环羧酚酸肽；钾离子载体，其可解偶联氧化磷酸化、诱导鼠胸腺细胞凋亡、抑制NGF诱导的神经元分化、并拮抗ET诱导的血管收缩。

其他说明

Keep container tightly closed in a dry and well-ventilated place. Hygroscopic.

基本信息

经验(实验)分子式C54H90N6O18
分子量1111.32
Beilstein78657
MDL编号MFCD00005114
PubChem化学物质编号24900743

产品性质

质量水平200
生物来源Streptomyces sp.
测定≥90% (HPLC)
形式liquid
储存条件 (Keep container tightly closed in a dry and well-ventilated place. Hydroscopic.)
浓度~1 mg/mL in DMSO
颜色 colorless
作用机制cell membrane | interferes
抗生素抗菌谱Gram-positive bacteria
parasites
viruses
运输wet ice
储存温度2-8℃
SMILES stringCC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C
InChI1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34-,35+,36+,37-,38-,39-,40+,41+,42+/m0/s1
InChI keyFCFNRCROJUBPLU-RPUZOQEISA-N

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)188.6 °F - closed cup
闪点(C)87 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9