| CAS: | 199850-67-4 | ||
| 分子式: | C17H18BrNO4S | ||
| 分子量: | 412.3 | ||
| 英文名称: |
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| 用途: | PD 166793 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor (IC50s = 6.1, 0.047, 0.012, 7.2, 7.9, 0.008, and 0.24 μM for MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13CD, and MMP-14CD, respectively). |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||
| P912006 | MACKLIN | PD 166793 | 98% | 1430元/5mg; | 展开 | ||||||||||||||||||||||||||||||||
储存：-20°C，密闭，干燥 | |||||||||||||||||||||||||||||||||||||
| 444284 | Sigma-Aldrich | MMP-2/MMP-3 Inhibitor III, PD166793-CAS 199850-67-4-Calbiochem | The MMP-2/MMP-3 Inhibitor III, PD166793, also referenced under CAS 199850-67-4, controls the biological activity of MMP-2/MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors | 3124.36元/5 MG; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 µM), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 µM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes. 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Irritant (B) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 其他说明 Paolocci, N., et al. 2006. J. Pharm. Exp. Ther.317, 506. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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