CAS 1997319-84-2; sgc-smarca-brdviii

CAS:

1997319-84-2

分子式:

C₁₉H₂₅N₅O₃

分子量:

371.43

英文名称:

sgc-smarca-brdviii

1,1-dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate

tert-butyl 4-[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazine-1-carboxylate

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

S983714

MACKLIN

SGC-SMARCA-BRDVIII

≥99%

1347元/5mg;

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储存：-20°C

SML3094

Sigma-Aldrich

SGC-SMARCA-BRDVIII

≥98% (HPLC)

1076.74元/5 MG; 4337.05元/25 MG;

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产品说明

生化/生理作用

SGC-SMARCA-BRDVIII is a potent, SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain (BRD) inhibitor that effectively blocks adipocyte differentiation in 3T3-L1 murine fibroblast cultures (1 μM) by preventing the expression of key adipogenesis genes, including PPARγ, C/EBPα, and FABP4, with a >10-fold higher potency than PFI-3.

基本信息

经验(实验)分子式	C₁₉H₂₅N₅O₃
分子量	371.43

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C(N1CCN(CC1)C2=C(N)N=NC(C3=CC=CC=C3O)=C2)OC(C)(C)C

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable