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CAS: 19794-97-9
分子式: C18H40NO5P
分子量: 381.5
英文名称: 
d-erythro-dihydrosphingosine 1-phosphate
用途: Sphinganine-1-phosphate is an intermediate in the metabolism of glycosphingolipids and sphingolipids. It acts as an antagonist at the sphingosine-1-phosphate (S1P1/EDG-1) receptor (Ki = 15 nM).
推荐供应商
货号品牌产品名称规格包装、参考价格详情
S911994MACKLINSphinganine-1-phosphate (d18:0)98%2417元/1mg;   展开
储存:-20°C,密闭,干燥
状态:淡米黄色到浅米黄色固体
D3439Sigma-AldrichD-erythro-Dihydrosphingosine 1-phosphate≥98% (TLC), waxy solid2579.1元/1 MG;   展开

产品说明

生化/生理作用

Negative control for sphingosine-1-phosphate.

基本信息

经验(实验)分子式C18H40NO5P
分子量381.49
MDL编号MFCD00871363
PubChem化学物质编号24893757

产品性质

质量水平200
测定≥98% (TLC)
形式waxy solid
颜色 yellow
溶解性methanol: THF: water (6:3:1): >0.5 mg/mL
储存温度−20℃
SMILES stringCCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O
InChI1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1
InChI keyYHEDRJPUIRMZMP-ZWKOTPCHSA-N
Gene Informationhuman ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
860536PAvantiSphinganine-1-Phosphate (d18:0)Avanti Polar Lipids 860536P, powder2646.54元/1 MG;   展开

产品说明

一般描述

Sphinganine-1-Phosphate (SA1P) is a bioactive lipid present in mammals. It is produced from the sphingoid base, sphinganine in the presence of sphingosine kinase (SPHK).

应用

Sphinganine-1-Phosphate (d18:0) has been used as a reference standard in ultra performance liquid chromatography coupled to a mass spectrometry. It is suitable for use as an internal standard for ultra high performance liquid chromatography for the quantification of blood and muscle sphingolipid. Sphinganine-1-phosphate (d18:0) is also suitable for use as standard in liquid chromatography tandem mass spectrometry.

生化/生理作用

Sphinganine-1-Phosphate (SA1P) is an important marker for cancer and immune system disorders studies. It elicits protective functionality in hepatic ischemia. Elevated levels of SA1P is observed in hepatocellular carcinoma.

包装

5 mL Amber Glass Screw Cap Vial (860536P-5mg)
5 mL Amber Glass Screw Cap Vial (860536P-1mg)

基本信息

经验(实验)分子式C18H40NO5P
分子量381.49
NACRESNA.25

产品性质

形式powder
包装pkg of 1 × 1 mg (860536P-1mg)
pkg of 1 × 5 mg (860536P-5mg)
manufacturer/tradenameAvanti Polar Lipids 860536P
运输dry ice
储存温度−20℃
SMILES string[H][C@](CCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O
InChI1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1
InChI keyYHEDRJPUIRMZMP-ZWKOTPCHSA-N

安全信息

储存分类代码13 - Non Combustible Solids
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