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关键词:       仅模糊查询
CAS: 19774-82-4
分子式: C25H30ClI2NO3
分子量: 681.78
中文名称: 
盐酸胺碘酮
英文名称: 
ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl, hyd
2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone hyd
amiodaronum hydrochloride
cordarone
l 3428
l 3428 labaz
skf 33134 a
trangorex
ketone, 2-butyl-3-benzofuranyl4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl, hydrochloride
用途: 抗心律失常、心绞痛药。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A792962MACKLIN胺碘酮盐酸盐10mM in DMSO820元/1ml;   展开
储存：-20°C
状态：白色至灰白色晶体粉末
A835233MACKLIN胺碘酮盐酸盐≥98%125元/1g;   305元/5g;   1036元/25g;   3349元/100g;   展开
储存：2~8°C,密封
状态：白色到灰白色晶体粉末
A2530TCIAmiodarone Hydrochloride>98.0%(T)(HPLC)460元/1G;   1115元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C25H29I2NO3・HCl = 681.78
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况光,加热
相关CAS RN1951-25-3
Reaxys-RN4776323
PubChem物质ID172088928
Merck Index (14)482
MDL编号MFCD00069204

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %

物性(参考值)

熔点156 ℃(dec.)
最大吸收波长242(MeOH) nm
水溶性不溶
在水中的溶解度700 mg/l   25 ℃
溶解性(可溶于)甲醇,氯仿
溶解性(微溶于)乙醇
溶解度(极微溶)四氢呋喃,苯
溶解性(不溶于)乙醚

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H361 : 怀疑对生育能力或胎儿造成伤害。
H362 : 可能对母乳喂养的儿童造成伤害。
H373 : 长期或反复接触可能损害器官。
H413 : 可能对水生生物造成长期持续有害影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P263 : 怀孕/ 哺乳期间避免接触。
P273 : 避免释放到环境中。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P308 + P313 : 如接触到或有疑虑：求医/就诊。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P405 : 存放处须加锁。

相关法规

RTECS#OB1361000
952163J&KAmiodarone Hydrochloride98%360元/100MG;   展开

基本信息

分子式C25H29I2NO3·HCl
分子量681.77
MDL编码MFCD00069204
A8423Sigma-AldrichAmiodarone Hydrochloride≥98%906.01元/1 G;   2764.15元/5 G;   5449.89元/10 G;   展开

产品说明

应用

盐酸胺碘酮是一种非选择性离子通道阻滞剂，具有广泛的杀真菌活性。胺碘酮诱导 Ca2+ 立即流入 酿酒酵母中，随后发生线粒体断裂和细胞死亡。盐酸胺碘酮也用于一项确定污水处理厂排出物中甲状腺干扰物质的浓度的研究。
盐酸胺碘酮用于研究其与半胱胺的相互作用，刺激培养的生物传感器细胞系发生自噬。也用于幼虫和成虫器官毒性基因组学筛选，分析药物的转录作用。

包装

1, 5, 10 g in poly bottle

生化/生理作用

具有广泛杀真菌活性的非选择性离子通道阻滞剂。胺碘酮诱导 Ca2+ 立即流入 酿酒酵母 中，随后发生线粒体断裂和细胞死亡。

特点和优势

该化合物由 Wyeth 开发 。要浏览其他制药公司开发的化合物列表批准的药物/候选药物的列表， 点击这里 。

底物

CYP2C8/9 和 CYP3A 家族(次要通路)抑制剂和底物；CYP2D6、CYP3A 家族、CYP2D6、CYP2A6、CYP2B6 去乙基形式抑制剂

基本信息

经验(实验)分子式C25H29I2NO3 · HCl
分子量681.77
EC 号243-293-2
MDL编号MFCD00069204
PubChem化学物质编号24277818
NACRESNA.77

产品性质

质量水平200
测定≥98%
创始人Wyeth
储存温度2-8℃
SMILES stringCl[H].CCCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3
InChI1S/C26H31I2NO3.ClH/c1-4-7-8-13-23-24(19-11-9-10-12-22(19)32-23)25(30)18-16-20(27)26(21(28)17-18)31-15-14-29(5-2)6-3;/h9-12,16-17H,4-8,13-15H2,1-3H3;1H
InChI keyDBZSHZLTNYTZJM-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语：Warning
危险声明H312 + H332 - H315 - H319 - H361d - H373 - H410
预防措施声明P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR1164SupelcoAmiodarone HydrochloridePharmaceutical Secondary Standard; Certified Reference Material941.08元/1 G;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Amiodarone hydrochloride is an antiarrhythmic drug used for the treatment of ventricular and supraventricular tachycardia.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Amiodarone hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography.

生化/生理作用

具有广泛杀真菌活性的非选择性离子通道阻滞剂。胺碘酮诱导 Ca2+ 立即流入 酿酒酵母 中，随后发生线粒体断裂和细胞死亡。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3555 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C25H29I2NO3 · HCl
分子量681.77
EC 号243-293-2
MDL编号MFCD00069204
PubChem化学物质编号329823181
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 532
traceable to PhEur A0575000
traceable to USP 1027302
储存温度2-8℃
SMILES stringCl[H].CCCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3
InChI1S/C26H31I2NO3.ClH/c1-4-7-8-13-23-24(19-11-9-10-12-22(19)32-23)25(30)18-16-20(27)26(21(28)17-18)31-15-14-29(5-2)6-3;/h9-12,16-17H,4-8,13-15H2,1-3H3;1H
InChI keyDBZSHZLTNYTZJM-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语：Warning
危险声明H312 + H332 - H315 - H319 - H361d - H373 - H410
预防措施声明P201 - P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
A0575000Amiodarone HydrochlorideEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

具有广泛杀真菌活性的非选择性离子通道阻滞剂。胺碘酮诱导 Ca2+ 立即流入 酿酒酵母 中，随后发生线粒体断裂和细胞死亡。

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C25H29I2NO3 · HCl
分子量681.77
MDL编号MFCD00069204
PubChem化学物质编号329770619
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl[H].CCCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3
InChI1S/C26H31I2NO3.ClH/c1-4-7-8-13-23-24(19-11-9-10-12-22(19)32-23)25(30)18-16-20(27)26(21(28)17-18)31-15-14-29(5-2)6-3;/h9-12,16-17H,4-8,13-15H2,1-3H3;1H
InChI keyDBZSHZLTNYTZJM-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语：Warning
危险声明H312 + H332 - H315 - H319 - H361d - H373 - H410
预防措施声明P201 - P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1027302USPAmiodarone HydrochlorideUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

具有广泛杀真菌活性的非选择性离子通道阻滞剂。胺碘酮诱导 Ca2+ 立即流入 酿酒酵母 中，随后发生线粒体断裂和细胞死亡。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C25H29I2NO3 · HCl
分子量681.77
MDL编号MFCD00069204
PubChem化学物质编号329748999
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl[H].CCCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3
InChI1S/C26H31I2NO3.ClH/c1-4-7-8-13-23-24(19-11-9-10-12-22(19)32-23)25(30)18-16-20(27)26(21(28)17-18)31-15-14-29(5-2)6-3;/h9-12,16-17H,4-8,13-15H2,1-3H3;1H
InChI keyDBZSHZLTNYTZJM-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语：Warning
危险声明H312 + H332 - H315 - H319 - H361d - H373 - H410
预防措施声明P260 - P280 - P305 + P351 + P338
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP532Amiodarone HydrochlorideBritish Pharmacopoeia (BP) Reference Standard1861.35元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

具有广泛杀真菌活性的非选择性离子通道阻滞剂。胺碘酮诱导 Ca2+ 立即流入 酿酒酵母 中，随后发生线粒体断裂和细胞死亡。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C25H29I2NO3 · HCl
分子量681.77
EC 号243-293-2
MDL编号MFCD00069204
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCl[H].CCCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3
InChI1S/C26H31I2NO3.ClH/c1-4-7-8-13-23-24(19-11-9-10-12-22(19)32-23)25(30)18-16-20(27)26(21(28)17-18)31-15-14-29(5-2)6-3;/h9-12,16-17H,4-8,13-15H2,1-3H3;1H
InChI keyDBZSHZLTNYTZJM-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语：Warning
危险声明H312 + H332 - H315 - H319 - H361d - H373 - H410
预防措施声明P260 - P280 - P305 + P351 + P338
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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