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CAS: 1968-05-4
分子式: C17H14N2
分子量: 246.31
中文名称: 
二(3,3'-吲哚基)甲烷
双吲哚甲烷
3,3'-二吲哚甲烷
英文名称: 
3,3'-Methylenebisindole
3,3'-diindolylmethane
Indole dimer
用途: 医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D830949MACKLIN3,3'-二吲哚甲烷98%29元/5g;   40元/25g;   110元/100g;   475元/500g;   展开
储存:室温,密封
状态:白色到灰白色粉末晶体
D797860MACKLIN3,3'-二吲哚甲烷10mM in DMSO185元/1ml;   展开
储存:-20°C
M1399TCI3,3'-Methylenediindole>98.0%(N)485元/5G;   1425元/25G;   展开

基本信息

纯度/分析方法>98.0%(N)
分子式/分子量C17H14N2 = 246.31
外观与形状(20℃)固体
Reaxys-RN223072
PubChem物质ID87573351
MDL编号MFCD00195766

技术规格

AppearanceWhite to Light yellow to Light red powder to crystal
Purity(HPLC)min. 97.0 area%
Purity(with Total Nitrogen)min. 98.0 %

物性(参考值)

熔点167 ℃
486069J&K3,3'-Diindolylmethane98%82元/1G;   326元/5G;   1302元/25G;   展开

基本信息

分子式C17H14N2
分子量246.31
MDL编码MFCD00195766
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
H413
防范说明P261
P305+P351+P338
WGK3
Y10465Alfa Aesar3,3'-Diindolylmethane176元/10g;   361元/25g;   855元/100g;   2213元/500g;   展开

基本信息

分子量
246.31

D9568Sigma-Aldrich3,3′-Diindolylmethane≥98% (HPLC)2107.44元/5 G;   展开

产品说明

包装

5 g in poly bottle

生化/生理作用

一种天然存在于十字花科吲哚-3-甲醇的植物化学物质的酸催化反应产物。其具有抗肿瘤作用。该衍生物既能直接刺激相对高浓度的细胞凋亡,又能增敏 TRAIL 诱导的人癌细胞凋亡。 DIM 诱导人乳腺癌 MCF-7 细胞 G 1 细胞周期阻滞的机制包括 p21 表达增加。DIM 是一种强的线粒体 H + -atp 酶抑制剂。已在环境友好系统中研究了 DIM 及其衍生物作为新型植物生长促进剂的作用。

基本信息

经验(实验)分子式C17H14N2
分子量246.31
MDL编号MFCD00195766
PubChem化学物质编号329798906
NACRESNA.25

产品性质

质量水平100
测定≥98% (HPLC)
储存温度2-8℃
SMILES stringC(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34
InChI1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
InChI keyVFTRKSBEFQDZKX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335 - H413
预防措施声明P273 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
74601Supelco3,3′-Diindolylmethaneanalytical standard2368.6元/100 MG;   展开

产品说明

一般描述

3,3′-二吲哚甲烷是吲哚-3-甲醇的二聚体,是十字花科蔬菜的成分。已知具有抗癌作用。

应用

3,3′-二吲哚甲烷可用作模型底物,以分析 3,3′二吲哚基甲烷在诱导人癌细胞凋亡中的作用。

生化/生理作用

一种天然存在于十字花科吲哚-3-甲醇的植物化学物质的酸催化反应产物。其具有抗肿瘤作用。该衍生物既能直接刺激相对高浓度的细胞凋亡,又能增敏 TRAIL 诱导的人癌细胞凋亡。 DIM 诱导人乳腺癌 MCF-7 细胞 G 1 细胞周期阻滞的机制包括 p21 表达增加。DIM 是一种强的线粒体 H + -atp 酶抑制剂。已在环境友好系统中研究了 DIM 及其衍生物作为新型植物生长促进剂的作用。

基本信息

经验(实验)分子式C17H14N2
分子量246.31
MDL编号MFCD00195766
NACRESNA.24

产品性质

等级analytical standard
质量水平100
测定≥97.5% (HPLC)
保质期limited shelf life, expiry date on the label
application(s)food and beverages
格式neat
储存温度2-8℃
SMILES stringC(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34
InChI1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
InChI keyVFTRKSBEFQDZKX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335 - H413
预防措施声明P273 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
024220FluorochemBis (3-indolyl)methane95%220元/10g;   440元/25g;   1210元/100g;   展开

基本信息

CAS Number1968-05-4
MDL NumberMFCD00195766
Melting Point167℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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