| CAS: | 196391-82-9 | ||||||
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||
| SML1417 | Sigma-Aldrich | Prosaptide Tx 14(A) trifluoroacetate salt | ≥95% (HPLC) | 1966.13元/1 MG; | 咨询 | ||||||||||||||||||||||||||
产品说明 包装 1 mg in glass bottle 生化/生理作用 Prosaptide Tx 14(A) is a potent agonist of G protein-coupled receptors GPR37 (also known as Parkin-associated endothelin receptor-like receptor Pael-R) and GPR37L1. Prosaptide Tx 14(A) is the active fragment of prosaposin, a secreted neuroprotective and glioprotective factor. Prosaptide Tx 14(A) has EC50 values of 5 nM for GPR37L1 and 7 nM for GPR37, and has also been shown to have some GSK3 inhibitory properties. Prosaptide has been shown to improve nerve regeneration in diabetic rats, to reduce neuropathic pain, and to protect dopaminergic neurons in animal models of Parkinson disease. 基本信息
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