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CAS: 1955554-64-9
英文名称: 
2-(piperidin-4-yl)benzoic acid hydrochloride
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916854Sigma-Aldrich2-(Piperidin-4-yl)benzoic acid hydrochloride95%2018.33元/100 MG;   展开

产品说明

应用

2-(Piperidin-4-yl)benzoic acid hydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.

其他说明

Portal: Building PROTAC® Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式C12H16ClNO2
分子量241.71
MDL编号MFCD08460728

产品性质

质量水平100
测定95%
形式powder
储存温度2-8℃
SMILES stringO=C(C1=C(C2CCNCC2)C=CC=C1)O.Cl
O=C(C1=C(C2CCNCC2)C=CC=C1)O.Cl

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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