CAS 185517-74-2; tvp1022

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CAS:

185517-74-2

分子式:

C₁₂H₁₃N

分子量:

171.24

英文名称:

tvp1022

(S)-rasagiline

s-(-)-n-propargyl-1-aminoindan

(1S)-2,3-dihydro-n-2-propyn-1-yl-1h-inden-1-amine

用途:

(S)-Rasagiline (TVP1022) 是 Rasagiline 的 S 型同分异构体。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

S881064

MACKLIN

(S)-Rasagiline

≥99%

545元/5mg; 881元/10mg; 2125元/50mg;

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储存：2-8℃
状态：浅黄色到黄色油状

SML0222

Sigma-Aldrich

TVP1022

≥98% (HPLC)

1306.9元/5 MG; 5250.73元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

TVP1022, the S-isomer of rasagiline, an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. TVP1022, a neuroprotective and cytoprotective molecule, is also cardioprotective in rat models. Its activity is believed to involve stabilization of mitochondrial membrane potential, induction of Bcl-2 and activation of the PKC signalling pathway, enhancing the phosphorylation of protein kinase C and glycogen synthase kinase-3β.

基本信息

经验(实验)分子式	C₁₂H₁₃N
分子量	171.24
MDL编号	MFCD09029306
PubChem化学物质编号	329825241
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
溶解性	DMSO: ≥15 mg/mL
储存温度	2-8℃
SMILES string	C#CCN[C@H]1CCc2ccccc12
InChI	1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m0/s1
InChI key	RUOKEQAAGRXIBM-LBPRGKRZSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H400
预防措施声明	P273 - P301 + P312 + P330
危险分类	Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

387561

Fluorochem

(S)-N-(2-PROPYNYL)-2,3-DIHYDROINDEN-1-AMINE

97%

4862元/250mg; 12122元/1g;

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基本信息

CAS Number	185517-74-2
MDL Number	MFCD09029306

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