CAS 185039-91-2; pd166326

CAS:

185039-91-2

分子式:

C₂₁H₁₆Cl₂N₄O₂

分子量:

427.3

英文名称:

pd166326

pd 166326

6-(2,6-dichlorophenyl)-2-[[3-(hydroxymethyl)phenyl]amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8h)-one

用途:

PD 166326 is a pyridopyrimidine-type inhibitor of receptor tyrosine kinases that inhibits c-abl (IC50 = 8 nM) and Bcr/Abl-dependent cell growth (IC50 = 0.4 nM).

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货号

品牌

产品名称

规格

包装、参考价格

详情

P911866

MACKLIN

PD 166326

98%

1248元/1mg;

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储存：-20°C，密闭，干燥

PZ0366

Sigma-Aldrich

PD166326

≥98% (HPLC)

1117.23元/5 MG; 4498.97元/25 MG;

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产品说明

生化/生理作用

ATP-competitive dual BCR-ABL and Src kinase inhibitor
PD166326 is an ATP-competitive dual BCR-ABL and Src kinase inhibitor. In some studies it has been found to be more potent than imatinib with inhibition of cancer growth in the low nanomolar range or even picomolar range in various biological systems.

法律信息

Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₁H₁₆Cl₂N₄O₂
分子量	427.28
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	white to light brown
溶解性	DMSO: 2 mg/mL, clear
创始人	Pfizer
储存温度	room temp
SMILES string	O=C1N(C)C2=C(C=NC(NC3=CC=CC(CO)=C3)=N2)C=C1C4=C(Cl)C=CC=C4Cl

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable