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CAS: 1775-95-7
分子式: C13H10N2O3
分子量: 242.23
熔点: 159-164℃
中文名称: 
2-氨基-5-硝基苯并苯酮
2-氨基-5-硝基二苯酮
(2-氨基-5-硝基苯基)苯基酮
2-氨基-5-硝基二苯甲酮
硝基氨基酮
英文名称: 
(2-amino-5-nitrophenyl)phenyl-Methanone
2-Benzoyl-4-nitroaniline
2-Amino-5-nitrodiphenylone
(2-amino-5-nitrophenyl)phenyl-methanon
(2-amino-5-nitrophenyl)phenylmethanone
2-amino-5-nitrobenzophenone
Methanone,(2-amino-5-nitrophenyl)phenyl-
2-Amino-5-nitrodiphenylmethone
2-amino-5-nitro diphenylone
性质描述: 该品为黄红色棱状结晶体。熔点161.5℃。溶于乙醇、乙酸。
生产方法: 由对硝基苯胺和苯甲酰氯缩合而得。将对硝基苯胺、苯甲酰氯和氯化锌加入反应罐内搅拌,加热使物料全部熔化。升温至140℃,保温30min。继续升温至200℃左右,保温反应2h,冷至115-120℃,搅拌水解15h。加入2.5倍稀盐酸,冷至35℃,过滤。滤饼用稀盐酸洗涤,滤干。加4倍量的水搅成糊状,加碱到pH为11,浸泡2-3h(浸泡过程中要补加碱,加碱到pH为11)。过滤,滤饼用水洗使pH为6-7。滤干,干燥得二苯酮粗品。加适量活性炭和10倍量的乙醇,加热回流4h。趁热过滤。滤液冷却结晶。甩滤,滤饼用冷乙醇洗涤,滤干,干燥即得。收率为25%。
用途: 用作医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A800147MACKLIN2-氨基-5-硝基二苯酮98%55元/25g;   214元/100g;   968元/500g;   展开
储存:室温
状态:黄色到棕色粉末
A1134TCI2-Amino-5-nitrobenzophenone>98.0%(HPLC)520元/25G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C13H10N2O3 = 242.23
外观与形状(20℃)固体
Reaxys-RN748830
PubChem物质ID87562618
SDBS (AIST Spectral DB)22495
MDL编号MFCD00007364

技术规格

AppearanceLight yellow to Yellow to Orange powder to crystal
Purity(HPLC)min. 98.0 area%
Melting point161.0 to 164.0 ℃

物性(参考值)

熔点163 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#PC4935000
284251J&K2-Amino-5-nitrobenzophenone99%315元/25G;   1037元/100G;   展开

基本信息

分子式C13H10N2O3
分子量242.23
熔点166-168
MDL编码MFCD00007364
Beilstein748830
EINECS 编号217-207-9

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSPC4935000
TSCA
956077J&K2-Amino-5-nitrobenzophenone98%310元/25G;   1030元/100G;   展开

基本信息

分子式C13H10N2O3
分子量242.23
熔点166-168
MDL编码MFCD00007364
Beilstein748830
EINECS 编号217-207-9

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSPC4935000
TSCA
B23773Alfa Aesar2-Amino-5-nitrobenzophenone98%252元/5g;   550元/25g;   3306元/100g;   展开

应用
It is used in the determination of nitrazepam in serum by gas-liquid chromatography; application in bioavailability studies and in second-harmonic generation in aromatic organic compounds.

备注
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00007364

EINECS
217-207-9

分子式
C13H10N2O3

分子量
242.23

熔点
166-168°

灵敏度
Ambient temperatures.

溶解性
Soluble in chloroform, dichloromethane, dimethyl sulfoxide, ethyl acetate and methanol. Soluble in water 3 mg/L (20°C).

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
PC4935000

TSCA

211737Sigma-Aldrich2-Amino-5-nitrobenzophenone≥98%483.83元/25 G;   1159.03元/100 G;   展开

产品说明

一般描述

FT-IR and Raman spectra of 2-amino-5-nitrobenzophenone (ANBP) has been reported.

应用

2-Amino-5-nitrobenzophenone was used in the synthesis of [5-(4-nitrophenyl)-2-furyl]acrylic acid substituted benzophenone (anti-malarial agent).

包装

25, 100 g in glass bottle

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 211737.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

线性分子式H2NC6H3(NO2)C(O)C6H5
分子量242.23
EC 号217-207-9
MDL编号MFCD00007364
PubChem化学物质编号24852702
NACRESNA.22

产品性质

质量水平100
测定≥98%
形式powder
mp166-168 ℃ (lit.)
SMILES stringNc1ccc(cc1C(=O)c2ccccc2)[N+]([O-])=O
InChI1S/C13H10N2O3/c14-12-7-6-10(15(17)18)8-11(12)13(16)9-4-2-1-3-5-9/h1-8H,14H2
InChI keyPZPZDEIASIKHPY-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
234390Fluorochem(2-Amino-5-nitrophenyl)(phenyl)methanone95%220元/1g;   242元/10g;   396元/25g;   792元/100g;   展开

基本信息

CAS Number1775-95-7
MDL NumberMFCD00007364
Melting Point163℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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