CAS 176977-56-3; ly 320135

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CAS:

176977-56-3

分子式:

C₂₄H₁₇NO₄

分子量:

383.40

英文名称:

ly 320135

4-[6-methoxy-2-(4-methoxyphenyl)benzofuran-3-carbonyl]benzonitrile

[6-methoxy-2-(4-methoxyphenyl)benzo[b]furan-3-yl](4-cyanophenyl)methanone

ly320135

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

L920702

MACKLIN

4-[6-甲氧基-2-(4-甲氧基苯基)苯并呋喃-3-羰基]苄腈

≥98% (HPLC)

942元/5mg;

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储存：2-8°C
状态：固体

L5295

Sigma-Aldrich

LY 320135

≥98% (HPLC)

1151.92元/5 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

LY320135 is a potent CB1 receptor antagonist/inverse agonist (Ki = 141 nM) with greater than 70-fold selectivity over CB2 receptors (Ki > 10 μM). Structurally dissimilar from SR 141716A and AM 251. Shows weak binding to both 5-HT2 (Ki = 6.4 μM) and muscarinic receptors (Ki = 2.1 μM)

特点和优势

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₂₄H₁₇NO₄
分子量	383.40
MDL编号	MFCD00945878
PubChem化学物质编号	329817622
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	orange
溶解性	DMSO: ≥10 mg/mL
创始人	Eli Lilly
储存温度	2-8℃
SMILES string	COc1ccc(cc1)-c2oc3cc(OC)ccc3c2C(=O)c4ccc(cc4)C#N
InChI	1S/C24H17NO4/c1-27-18-9-7-17(8-10-18)24-22(20-12-11-19(28-2)13-21(20)29-24)23(26)16-5-3-15(14-25)4-6-16/h3-13H,1-2H3
InChI key	RYNSGDFWBJWWSZ-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301
预防措施声明	P301 + P310
危险分类	Acute Tox. 3 Oral
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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