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CAS: 173897-44-4
分子式: C16H16N4O·2HCl
分子量: 353.25
英文名称: 
y-33075 dihydrochloride
用途: Y-39983是选择性ROCK抑制剂,IC50为3.6 nM。
推荐供应商
货号品牌产品名称规格包装、参考价格
Y873128MACKLINY-39983 HCl99%332元/1mg;   915元/5mg;   咨询
储存:-20℃
状态:白色到灰色固体
Y798214MACKLINY-39983 HCl10mM in DMSO1061元/1ml;   咨询
储存:-20°C
SML2920Sigma-AldrichY-39983 dihydrochloride≥98% (HPLC)833.87元/5 MG;   3365.56元/25 MG;   咨询

产品说明

生化/生理作用

Y-39983 is a potent and selective Rho-kinase (ROCK) inhibitor (IC50s = 3.6 nM). Y-39983 is 10 fold more potent in promoting the outgrowth of neurites in cultured retinal slices and axonal regeneration in crushed optic nerve models than Y-27632. Y-39983 act also as an activator of the neuroprotective Parkin-mediated mitophagy pathway.

基本信息

经验(实验)分子式C16H16N4O · 2HCl
分子量353.25
MDL编号MFCD00945328

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
旋光性[α]/D +5 to +9°, c = 1 in methanol
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃
SMILES stringN[C@@H](C1=CC=C(C(NC2=CC=NC3=C2C=CN3)=O)C=C1)C.Cl.Cl

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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