| CAS: | 173436-66-3 | ||||
| 分子式: | C15H15NO4S | ||||
| 分子量: | 305.35 | ||||
| 沸点: | 456.5±55.0°C(Predicted) | ||||
| 熔点: | 152-154 °C | ||||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||
| M918691 | MACKLIN | 3-(4-甲基苯基磺酰胺基)苯甲酸甲酯 | 98% | 50元/1mg; 99元/5mg; 136元/25mg; 302元/100mg; 509元/250mg; | 展开 | ||||||||||||||||||||||||||||||
储存：2-8°C 状态：白色到灰白色到浅紫色到紫色粉末 | |||||||||||||||||||||||||||||||||||
| M795966 | MACKLIN | 3-(4-甲基苯基磺酰胺基)苯甲酸甲酯 | 10mM in DMSO | 648元/1ml; | 展开 | ||||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||||
| SML1726 | Sigma-Aldrich | MSAB | ≥95% (HPLC) | 1562.86元/5 MG; 6299.25元/25 MG; | 展开 | ||||||||||||||||||||||||||||||
产品说明 包装 5, 25 mg in glass bottle 生化/生理作用 A cell-permeable compound that targets β-catenin via direct affinity interaction within the C-terminal two thirds (a.a. 301-670) of the Armadillo repeat region (a.a. 136–686), inducing β-catenin ubiquitination and proteasomal degradation (Eff. conc. 1.25-5 μM in DLD-1, SW480 and LS174T cultures). MSAB selectively inhibits against Wnt sginaling-dependent proliferation of cancer cells (IC50 <6 μM), while exhibiting little efficacy in Wnt-independent cultures (<10% inhibition at 10 μM). Likewise, daily intraperitoneal injection (10-20 mg/kg/day) is efficacious in suppressing the expansion of established tumors from HCT116, HT115, and H23 xenografts in mice, while exhibiting little efficacy against the Wnt-independent H460 tumor growth. 基本信息
产品性质
安全信息
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