CAS 172649-40-0; zd0947

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CAS:

172649-40-0

英文名称:

zd0947

3-[(4S)-1,4,5,6,7,8-hexahydro-5-oxo-2-(trifluoromethyl)-4-quinolinyl]-benzonitrile

3-[(4 s)5-oxo-2-(trifluoromethyl)-1,4,5,6,7,8-hexahydroquinolin-4-yl] benzonitrile

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货号

品牌

产品名称

规格

包装、参考价格

详情

SML2055

Sigma-Aldrich

ZD0947

≥98% (HPLC)

1734.82元/5 MG; 6985.55元/25 MG;

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产品说明

生化/生理作用

ZD0947 is potent ATP-sensitive K+ channels (KATP channels) opener. ZD0947 is an effective activator of smooth muscle-type KATP channels (SUR2B/Kir6.1 and SUR2B/Kir6.2) but is a partial antagonist of pancreatic-type KATP channels (i.e. SUR1/Kir6.2) and cardiac-type KATP channels (i.e. SUR2A/Kir6.2). ZD0947 potently inhibits carbacho-induced contraction in the strips of human detrusor.

基本信息

经验(实验)分子式	C₁₇H₁₃F₃N₂O
分子量	318.29
MDL编号	MFCD00944017
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -625 to -575°, c = 0.5 in methanol
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C1C2=C(NC(C(F)(F)F)=C[C@H]2C3=CC(C#N)=CC=C3)CCC1

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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