CAS 168021-79-2; 神经保护药物 nxy 059; nxy-059

位置：首页 > 资料中心 > 化工字典 > 168021-79-2

CAS:

168021-79-2

分子式:

C₁₁H₁₄NNa₂O₇S₂

分子量:

382.34

中文名称:

神经保护药物 nxy 059

英文名称:

nxy-059

disufenton sodium

1,3-benzenedisulfonic acid, 4-[[(1,1-dimethylethyl)imino]methyl]-, n-oxide, disodium salt

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

N796299

MACKLIN

NXY-059

10mM in DMSO

136元/1ml;

展开

储存：-20°C

SML2163

Sigma-Aldrich

HPN-07

≥98% (HPLC)

1073.15元/5 MG; 4355.38元/25 MG;

展开

产品说明

生化/生理作用

Originally characterized for its NO-mimicking activity in preventing peroxynitrite formation and in vivo neuroprotective efficacy in animal models of cerebral ischemia (100 mg/kg i.v. in rabbits; 30-60 mg/kg plus 30-60 mg/kg/h i.v. or 50 mg/kg plus 8.8 mg/kg/h s.c. in rats; 28 mg/kg plus 16 mg/kg/h i.v. in monkeys), OKN-007 (HPN-07, NXY-059) is an orally available α-phenyl-tert-butylnitrone (PBN) derivative that is also shown to exhibit sulfatase 2 (SULF2) inhibitory activity and anticancer efficacy both in cultures (effective conc. 170-200 μM in Huh7 heptoma cultures) and in several rodent glioma models in vivo (C6, RG2, and GL261; 75 mg/kg/day for rats and 168 mg/kg/day for mice via drinking water).

基本信息

经验(实验)分子式	C₁₁H₁₃NO₇S₂ · 2Na
分子量	381.33
MDL编号	MFCD09833648

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 2 mg/mL, clear
储存温度	−20℃
SMILES string	[O-]/[N+](C(C)(C)C)=C\C(C=CC(S([O-])(=O)=O)=C1)=C1S([O-])(=O)=O.[Na+].[Na+]
InChI	1S/C11H15NO7S2.2Na/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19;;/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19);;/q;2*+1/p-2
InChI key	XLZOVRYBVCMCGL-UHFFFAOYSA-L

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

468364

Fluorochem

CEROVIVE (NXY-059)

95%

5940元/250mg; 14828元/1g;

展开

基本信息

CAS Number	168021-79-2
MDL Number	MFCD09833648

CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9