CAS 1670-87-7; 1h-吲哚-5-甲酰胺; 1h-indole-5-carboxamide

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货号

品牌

产品名称

规格

包装、参考价格

详情

S933544

MACKLIN

SD-169

≥98%

240元/100mg; 367元/250mg; 989元/1g;

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储存：2-8°C，避光，干燥，密封

Y10352

Alfa Aesar

SD-169

5984元/100mg; 871元/250mg; 2261元/1g;

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基本信息

分子量
160.18

506158

Sigma-Aldrich

p38 MAP Kinase Inhibitor VII, SD-169-CAS 1670-87-7-Calbiochem

The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase.

2741.8元/10 MG;

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产品说明

一般描述

A cell-permeable indole compound that acts as a potent, ATP-competitive, and isozyme-selective p38α MAP kinase inhibitor (IC₅₀ = 3.2 nM). It inhibits p38β only at much higher concentrations (IC₅₀ = 122 nM) and exhibits little activity against p38γ, ERK2, JNK-1, or MAPKAPK-2 even at concentrations as high as 50 µM. When administered to NOD mice via food intake in vivo, SD-169 is shown to prevent the development of type 1 diabetes in prediabetic mice and display therapeutic efficacy in treating animals already in mild and moderate hyperglycemic states.

包装

10 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Harmful (C)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Medicherla, S., et al. 2006. J. Pharmacol. Exp. Ther.318, 99.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₉H₈N₂O
分子量	160.17
MDL编号	MFCD07779486

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	off-white
溶解性	water: 1 mg/mL DMSO: 10 mg/mL
运输	ambient
储存温度	2-8℃

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H319 - H335
预防措施声明	P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

050330

Fluorochem

1H-Indole-5-carboxamide

97%

1298元/250mg; 2838元/1g; 10824元/5g; 32472元/25g;

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基本信息

CAS Number	1670-87-7
MDL Number	MFCD07779486

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .