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CAS: 1660-94-2
分子式: C9H22O6P2
分子量: 288.22
沸点: 171-174°C 11mm Hg (Lit.)
中文名称: 
四乙基亚甲基二磷酸脂
英文名称: 
tetraethyl methylenediphosphonate
methylenedi-phosphonic aci tetraethyl ester
methylenebis(diethylphosphonate)
methylenedi(phosphonic acid) tetraethyl ester
methylenebis-phosphonic aci tetraethyl ester
methanediyl-bis-phosphonic acid tetraethyl ester
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T832776MACKLIN四乙基亚甲基二磷酸酯≥98%30元/1ml;   85元/5ml;   298元/25ml;   1189元/100ml;   展开
储存:室温,干燥,密封
状态:澄清无色到黄色液体
538005J&KTetraethyl methylenediphosphonate97%222元/1ML;   848元/5ML;   3327元/25ML;   展开

基本信息

分子式C9H22O6P2
分子量288.22
沸点171-174
闪点110
密度1.16
折光率(n20D)1.4420
MDL编码MFCD00039887
Beilstein1813241
EINECS 编号216-764-5

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSSZ9150000
TSCA
A14532Alfa AesarTetraethyl methylenediphosphonate98+%1615元/5g;   6901元/25g;   23594元/100g;   展开

应用
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00039887

EINECS
216-764-5

分子式
C9H22O6P2

分子量
288.22

沸点
151-153°/1.2mm

闪点
>110°(230°F)

密度
1.162

折射率
1.4400

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Slightly miscible with water.

Beilstein
1813241

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319
Causes skin irritation.Causes serious eye irritation.

Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36/38
Irritating to eyes and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
SZ9150000

TSCA

C30882Alfa AesarTetraethyl methylenediphosphonate97%1594元/5ml;   6644元/25ml;   展开

基本信息

Ref#
30882

MDL
39887

分子式
C9 H22 O6 P2

分子量
288.25

闪点
>110

密度
1.16

形态
Colorless to pale yellow liquid

359181Sigma-AldrichTetraethyl methylenediphosphonate97%774.67元/5 ML;   3310.73元/25 ML;   展开

产品说明

应用

用于合成以下物质的反应物:

  • 3-脱氧-D-阿拉伯糖-庚酸7-磷酸合酶的双重底物位点抑制剂
  • 含有宝石双膦酸酯的非天然α-氨基酸衍生物
  • 联苯磺酰氨基Me双膦酸作为基质金属蛋白酶和骨吸收的抑制剂
  • 通过Wittig-Horner反应生成番茄红素
  • 烷基氨基乙基双次膦酸靶向法呢基二磷酸合成酶
  • 用作香叶基香叶基二磷酸合成酶抑制剂的芳族双膦酸酯

用于抑制L-选择素的树突状聚甘油阴离子的合成前体

包装

5, 25 mL in glass bottle

基本信息

线性分子式CH2[P(O)(OCH2CH3)2]2
分子量288.21
Beilstein1813241
EC 号216-764-5
MDL编号MFCD00039887
PubChem化学物质编号24862057
NACRESNA.22

产品性质

质量水平200
测定97%
reaction suitabilityreaction type: C-C Bond Formation
折射率n20/D 1.442 (lit.)
bp171-174 ℃/11 mmHg (lit.)
密度1.16 g/mL at 25 ℃ (lit.)
SMILES stringCCOP(=O)(CP(=O)(OCC)OCC)OCC
InChI1S/C9H22O6P2/c1-5-12-16(10,13-6-2)9-17(11,14-7-3)15-8-4/h5-9H2,1-4H3
InChI keySTJWVOQLJPNAQL-UHFFFAOYSA-N

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
个人防护装备Eyeshields, Gloves, type ABEK (EN14387) respirator filter
386818FluorochemTetraethyl methylenediphosphonate97%220元/1g;   902元/5g;   3124元/25g;   11594元/100g;   展开

基本信息

CAS Number1660-94-2
MDL NumberMFCD00039887
Boiling Point171-174℃
Density1.16

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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