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关键词:       仅模糊查询
CAS: 16595-80-5
分子式: C11H12N2S·HCl
分子量: 240.76
熔点: 266-267 °C(lit.)
中文名称: 
左旋(四)咪唑
(S)-6-苯基-2,3,5,6-四氢-咪唑[2,1-B]噻唑单盐酸盐
左旋咪唑
L-2,3,5,6-四氢-6-苯基咪唑[2,1-6]噻唑盐酸盐
盐酸左旋咪唑
左咪唑
左旋四咪唑
驱虫速
左旋咪唑盐酸盐
(S)-(-)-2,3,5,6-四氢-6-苯基咪唑并[2,1-b]噻唑盐酸盐
(S)-(-)-6-苯基-2,3,5,6-四氢咪唑并[2,1-b]噻唑盐酸盐
展开更多中文名
英文名称: 
Levamisol hydrochloride
(-)-Tetramisole hydrochloride
(S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride
(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Hydrochloride
(-)-Tetramizole Hydrochloride
1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-Imidazo[2
1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, l-(-)-imidazo(
(-)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole hydrochloride
citarin l
decaris
1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-imidazo(
kw-2-le-t
l-(-)-2,3,5,6-tetrahydro-6-phenyl-imidazo(2,1-b)thiazole hydrochloride
l-tetramisole hydrochloride
levamisole hydrochloride
levomysol hydrochloride
niratic hydrochloride
niratic-puron hydrochloride
nsc-177023
r-12,564
ripercol-l
solaskil
stimamizol hydrochloride
tramisol
tramisole
worm-chek
1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride, l-(-)-imidazo(
Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-
L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole
Nemicide
展开更多英文名
性质描述: 白色或微黄色结晶性粉末。熔点227-229℃。易溶于氯仿,难溶于丙酮。无臭,味苦。
生产方法: 由消旋四咪唑(C11H12N2S,[5036-02-2])拆分、碱析、成盐而得。将双苯甲酰基-D-酒石酸酐与水煮沸,水解40min。降温至45℃左右,用氢氧化钠溶液把pH调节至7.5,加入消旋四咪唑。保温半小时后降温至10℃,过滤,水洗,得左旋咪唑对苯甲酰基酒石酸盐。用氢氧化钠溶液把pH调至9,过滤,水洗得左旋咪唑。用盐酸将pH调至3-4,加活性炭脱色,过滤,滤液浓缩至干,加丙酮冷却至0℃。析出结晶。过滤,干燥得左旋咪唑盐酸盐。分离对苯甲酰基酒石酸右旋咪唑盐时,所得的母液为右旋咪唑游离碱的混合液,进行消旋即得到消旋四咪唑。消旋四咪唑也可采用对甲苯磺酰谷氨酸或右旋樟脑磺酸进行拆分。
用途: 该品是驱肠虫药。左旋咪唑的活性约为消旋体的两倍,毒性及副作用也较低。左旋咪唑能使蛔虫肌肉麻痹后随粪便排出体外。主要用于抗蛔虫及抗钩虫。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
L798479MACKLIN盐酸左旋咪唑溶液100μg/mL in Methanol113元/1ml;   展开
储存:室温
L796785MACKLIN盐酸左旋咪唑10mM in H2O205元/1ml;   展开
储存:-20°C
状态:液体
L812625MACKLIN盐酸左旋咪唑99%45元/5g;   95元/25g;   296元/100g;   898元/500g;   3125元/2.5kg;   展开
储存:2~8°C
状态:白色固体
折射率:-126 ° (C=1, H2O)
L0231TCILevamisole Hydrochloride [for Biochemical Research]>99.0%(T)315元/1G;   640元/5G;   展开

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C11H12N2S・HCl = 240.75
外观与形状(20℃)固体
Reaxys-RN4358988
PubChem物质ID125307737
Merck Index (14)5459
MDL编号MFCD00012675

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 99.0 %
Melting point226.0 to 234.0 ℃
Specific rotation [a]20/D-122.0 to -130.0 deg(C=1, H2O)
Phosphatase inhibition testto pass test

物性(参考值)

熔点230 ℃
比旋光度 [α]D-126° (C=1,H2O)
水溶性可溶

安全信息

图形或危害标志
信号词危险
危险性说明H301 : 吞咽会中毒。
H372 : 长期或反复接触会对器官造成损害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P314 : 如感觉不适,须求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#NJ5960000

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
T1215TCILevamisole Hydrochloride>99.0%(T)250元/10G;   490元/25G;   展开

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C11H12N2S・HCl = 240.75
外观与形状(20℃)固体
Reaxys-RN4358988
PubChem物质ID87576994
Merck Index (14)5459
MDL编号MFCD00012675

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 99.0 %
Melting point226.0 to 234.0 ℃
Specific rotation [a]20/D-122 to -130 deg(C=1, H2O)
Solubility in Watervery faint turbidity

物性(参考值)

熔点230 ℃
比旋光度 [α]D-126° (C=1,H2O)
水溶性可溶

安全信息

图形或危害标志
信号词危险
危险性说明H301 : 吞咽会中毒。
H372 : 长期或反复接触会对器官造成损害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P314 : 如感觉不适,须求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#NJ5960000

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
340612J&KLevamisole Hydrochloride99%342元/10G;   1364元/50G;   展开

基本信息

分子式C11H12N2S·HCl
分子量240.76
熔点228-230
比旋光度([α]20D)-130 to -122 (C=1, H2O)
MDL编码MFCD00012675
Beilstein4358988
Merck14,5459
EINECS 编号240-654-6

安全信息

图形或危害标志
提示语Danger
危险说明H301
防范说明P301+P310
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSNJ5960000
Y0000047Levamisole hydrochloride for system suitabilityEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

包装

Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
Beilstein4358988
MDL编号MFCD00012675
PubChem化学物质编号329830827
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp228-230 ℃
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P330 + P331 + P310
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
L0380000Levamisole HydrochlorideEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

本产品按照现行药典要求提供和指定。所有本产品相关的支持信息,包括 SDS 和任何产品信息小册子,均由药典颁发机构制定和发布。 如需进一步信息和支持,请访问现行药典网站。

生化/生理作用

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

包装

单位量:20 mg。如有更改,恕不另行通知。按照发布药典提供的产品进行交付。对于当前的单位数量,请访问 EDQM 对照品目录目录 。

注意

请参见 由EDQM提供的SDS。。

其他说明

销售限制可能适用。

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
Beilstein4358988
EC 号240-654-6
MDL编号MFCD00012675
PubChem化学物质编号329817357
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp228-230 ℃
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1359302USPLevamisole HydrochlorideUnited States Pharmacopeia (USP) Reference Standard2633.96元/125 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
Beilstein4358988
MDL编号MFCD00012675
PubChem化学物质编号329750032
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp228-230 ℃
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P330 + P331 + P310
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
L9756Sigma-Aldrich(-)-Tetramisole Hydrochloride≥99% (GC)612.14元/5 G;   1068.89元/10 G;   展开

产品说明

包装

5, 10 g in poly bottle

应用

适用于抑制各种哺乳动物碱性磷酸酶(例如,肝、肾、胎盘、骨和肿瘤)。
肠道碱性磷酸酶仅受到轻微抑制。
不适合兽医使用。

生化/生理作用

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

其他说明

盐酸左旋咪唑可以 50mg/mL的浓度溶于水,产生澄清、无色的溶液。 在2-8℃ 下,溶液稳定保存约 1个月。

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
Beilstein4358988
EC 号240-654-6
MDL编号MFCD00012675
PubChem化学物质编号24278526
NACRESNA.77

产品性质

质量水平200
生物来源synthetic (organic)
测定≥99% (GC)
形式powder
mp228-230 ℃
溶解性water: 50 mg/mL, clear, colorless to faintly yellow
作用机制enzyme | inhibits
抗生素抗菌谱parasites
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310 + P330
危险分类Acute Tox. 3 Oral
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
BP212Levamisole HydrochlorideBritish Pharmacopoeia (BP) Reference Standard2582.06元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
MDL编号MFCD00012675

产品性质

等级pharmaceutical primary standard
质量British Pharmacopoeia (BP) Reference Standard
manufacturer/tradenameBP
mp230-233 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P264 - P270 - P301 + P310 + P330 - P405 - P501
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR1798SupelcoLevamisole HydrochloridePharmaceutical Secondary Standard; Certified Reference Material2472.38元/250 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Levamisole Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by potentiometric sensing, spectrometric and atomic absorption spectroscopy methods.

生化/生理作用

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3172 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
Beilstein4358988
EC 号240-654-6
MDL编号MFCD00012675
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 250 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp228-230 ℃
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 212
traceable to PhEur L0380000
traceable to USP 1359302
储存温度2-30℃
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310 + P330
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
31742SupelcoLevamisol hydrochlorideVETRANAL®, analytical standard833.42元/250 MG;   展开

产品说明

一般描述

盐酸左旋咪唑是一种具有免疫调节和抗癌属性的驱虫药。本品为白色结晶化合物,在酸性水溶液中稳定,在碱性/中性溶液中水解。

应用

有关合适仪器技术的更多信息,请参考产品 分析证书。如需进一步支持,请联系技术服务。
盐酸左旋咪唑可用作超高压液相色谱-串联质谱法测定牛奶样品中兽药残留的抗生素标准品。

生化/生理作用

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C11H12N2S · HCl
分子量240.75
Beilstein4358988
EC 号240-654-6
MDL编号MFCD00012675
PubChem化学物质编号329753914
NACRESNA.24

产品性质

等级analytical standard
质量水平100
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp228-230 ℃
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES stringCl.C1CN2C[C@@H](N=C2S1)c3ccccc3
InChI1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI keyLAZPBGZRMVRFKY-HNCPQSOCSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P264 - P270 - P301 + P310 - P405 - P501
危险分类Acute Tox. 3 Oral
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
094384Fluorochem(-)-Tetramisole Hydrochloride95%220元/1g;   220元/10g;   352元/25g;   展开

基本信息

CAS Number16595-80-5
MDL NumberMFCD00012675
Melting Point228-230℃

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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