CAS 1631164-24-3; (2S)-n-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-cyclopropyl-1-(4-fluorophenyl)sulfonyl-1′,1′-dioxo-spiro[indoline-3,4′-thiane]-5-carboxamide; bay-784

CAS:

1631164-24-3

中文名称:

(2S)-n-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-cyclopropyl-1-(4-fluorophenyl)sulfonyl-1′,1′-dioxo-spiro[indoline-3,4′-thiane]-5-carboxamide

英文名称:

bay-784

(2S)-n-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-2-cyclopropyl-1-[(4-fluorophenyl)sulfonyl]-1,2,2?,3?,5?,6?-hexahydro-spiro[3h-indole-3,4?-[4h]thiopyran]-5-carboxamide 1?,1?-dioxide

bay-1214784

bay 1214784

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货号

品牌

产品名称

规格

包装、参考价格

详情

SML3025

Sigma-Aldrich

BAY-784

≥98% (HPLC)

1272.2元/5 MG; 5100.38元/25 MG;

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产品说明

生化/生理作用

BAY-784 is an orally available, non-toxic, potent, and selective antagonist of human Gonadotropin-Releasing Hormone Receptor [hGnRH-R], which is potently active in other species including rate, dogs and cynomolgus monkey. It partially lowered plasma luteinizing hormone levels in humans. BAY-784 exhibits favorable drug metabolism and pharmacokinetic (DMPK) profile thus is suitable for in vivo studies.

基本信息

经验(实验)分子式	C₂₉H₂₆ClF₄N₃O₅S₂
分子量	672.11

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -120 to -100°, c = 0.5 in chloroform-d
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	O=S(CCC1(C2=C(N3S(C4=CC=C(F)C=C4)(=O)=O)C=CC(C(NCC5=C(Cl)C=C(C(F)(F)F)C=N5)=O)=C2)[C@@H]3C6CC6)(CC1)=O

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable