| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| L813610 | MACKLIN | L-蛋氨酸亚砜亚胺 | 98% | 381元/250mg; 705元/500mg; 1196元/1g; 4072元/5g; | 咨询 |
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| 981073 | J&K | L-Methionine sulfoximine | 97% | 802元/250MG; 1913元/1G; | 咨询 |
基本信息 | 分子式 | C5H12N2O3S | | 分子量 | 180.23 | | 熔点 | 210 | | 比旋光度([α]20D) | +10.8 to +14 (C=1, H2O) | | MDL编码 | MFCD00002621 | | 存储条件 | Store at 2-8℃ |
安全信息 | 图形或危害标志 |  | | 提示语 | Warning | | 危险说明 | H315
H319
H335 | | 防范说明 | P261
P305+P351+P338 |
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| C22720 | Alfa Aesar | L-Methionine sulfoximine | 98+% ACROS Organics | 1476元/250mg; 4251元/1g; 15048元/5g; | 咨询 |
基本信息 Ref#
22720 MDL
MFCD00002621 EINECS
629-483-1 分子式
C5 H12 N2 O3 S 分子量
180.22 熔点
210.0° 形态
White crystalline powder 安全信息 TSCA
否 |
| M5379 | Sigma-Aldrich | L-Methionine sulfoximine | | 1622.12元/250 MG; 2604.53元/500 MG; 3864.6元/1 G; 13349.2元/5 G; | 咨询 |
产品说明 应用 L-甲硫氨酸亚砜亚胺已被用作谷氨酰胺合成酶(GS)活性的一种有效抑制剂。 包装 250, 500 mg in poly bottle
1, 5 g in poly bottle 生化/生理作用 As a potent inhibitor of glutamine synthetase activity (GS), this reagent has widely been used as a selection agent for plasmid integration in Chinese hamster ovary (CHO) and other mammalian cell lines. The growing demand for high yield cell banks for production of recombinant proteins for therapeutics has resulted in two major systems for selection of stable and active clones, Methotrexate selection of dihydrofolate reductase (DHFR) overexpressing cells and MSX selection of glutamine synthetase overexpressing cells. Cells are grown in the absence of glutamine in the media and inhibition of the endogenous activity of glutamine synthetase results in cell death for cells lacking overexpression. The MSX-glutamine synthetase selection mechanism provides benefits over that of the Methotrexate-DHFR system in that it typically requires a single amplification step and results in significant reduction of time to produce high stability, highly amplified clones. L-Methionine sulfoximine (MSX) enhances NH3 production in seedling leaves wheat, barley, corn and sorghum plants by inhibiting GS activity. MSX increases ornithine decarboxylase activity and decreases the survival rate in a model of transient cerebral ischemia. 基本信息 | 线性分子式 | CH3S(O)(=NH)CH2CH2CH(NH2)CO2H | | 分子量 | 180.23 | | Beilstein | 6175446 | | MDL编号 | MFCD00002621 | | PubChem化学物质编号 | 24278555 | | NACRES | NA.32 |
产品性质 | 质量水平 | 300 | | mp | >210 ℃ (dec.) (lit.) | | SMILES string | CS(=N)(=O)CC[C@H](N)C(O)=O | | InChI | 1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1 | | InChI key | SXTAYKAGBXMACB-DPVSGNNYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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| 91016 | Supelco | L-Methionine sulfoximine | certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 5938.87元/100 mg; | 咨询 |
产品说明 一般描述 该认证标准物质(CRM)根据ISO/IEC 17025和ISO 17034进行生产和认证。该CRM可追溯来自NMI的原始材料，如NIST或NMIJ。
通过定量NMR获得的认证内容包括不确定性和失效日期，可在证书上找到。
证书下载网址：http://www.sigma-aldrich.com 应用 有关合适仪器技术的更多信息，请参考产品′分析证书。如需进一步支持，请联系技术服务部门。 包装 无底玻璃瓶。内含物装在插入的融合锥内。 法律信息 TraceCERT is a registered trademark of sigma-aldrich Co. LLC 基本信息 | 线性分子式 | CH3S(O)(=NH)CH2CH2CH(NH2)CO2H | | 分子量 | 180.23 | | Beilstein | 6175446 | | MDL编号 | MFCD00002621 | | PubChem化学物质编号 | 329769992 | | NACRES | NA.24 |
产品性质 | 质量水平 | 300 | | 等级 | certified reference material
TraceCERT® | | 产品线 | TraceCERT® | | 保质期 | limited shelf life, expiry date on the label | | analyte chemical class(es) | amino acids, peptides, proteins | | technique(s) | HPLC: suitable
gas chromatography (GC): suitable | | 颜色 | white | | mp | >210 ℃ (dec.) (lit.) | | application(s) | food and beverages | | 格式 | neat | | 储存温度 | 20-25℃ | | SMILES string | CS(=N)(=O)CC[C@H](N)C(O)=O | | InChI | 1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1 | | InChI key | SXTAYKAGBXMACB-DPVSGNNYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 104309 | SAFC | L-Methionine sulfoximine | EMPROVE® ESSENTIAL | 32288.6元/1 G; 80775.8元/5 G; 148548元/10 G; | 咨询 |
产品说明 联系 Emprove® 文件 法律信息 Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 线性分子式 | CH3S(O)(=NH)CH2CH2CH(NH2)CO2H | | 分子量 | 180.23 | | Beilstein | 6175446 | | MDL编号 | MFCD00002621 |
产品性质 | 质量水平 | 500 | | 产品线 | EMPROVE® ESSENTIAL | | 形式 | solid | | 包装 | pkg of 10g (1043090010)
pkg of 1g (1043090001)
pkg of 5g (1043090005)
pkg of | | mp | >210 ℃ (dec.) (lit.) | | 适用性 | suitable for manufacturing use | | SMILES string | CS(=N)(=O)CC[C@H](N)C(O)=O | | InChI | 1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1 | | InChI key | SXTAYKAGBXMACB-DPVSGNNYSA-N |
安全信息 | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 367480 | Fluorochem | 2-amino-4-(S-methylsulfonimidoyl)butanoic acid | | 9636元/1g; | 咨询 |
基本信息 | CAS Number | 15985-39-4 | | MDL Number | MFCD00063094 | | Melting Point | >210℃ |
安全信息 | 图形或危害标志 | | | 危险性说明 | H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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