[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 1576-37-0
关键词:       仅模糊查询
CAS: 1576-37-0
分子式: C14H15NO2S
分子量: 261.34
熔点: 115° C
英文名称: 
n-benzyl-p-toluenesulfonamid
4-methyl-n-(phenylmethyl)-benzenesulfonamid
n-benzyl-p-toluenesulfonamide
n-tosylbenzylamine
推荐供应商
货号品牌产品名称规格包装、参考价格
N863760MACKLINN-苄基-对甲苯磺酰胺98.0%(HPLC)44元/1g;   139元/5g;   491元/25g;   1664元/100g;   咨询
储存:室温
状态:白色到几乎白色粉末到晶体
B3082TCIN-Benzyl-p-toluenesulfonamide>98.0%(HPLC)(N)390元/5G;   1090元/25G;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)(N)
分子式/分子量C14H15NO2S = 261.34
外观与形状(20℃)固体
Reaxys-RN2217277
PubChem物质ID87560249
MDL编号MFCD00159328

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 98.0 %
Melting point113.0 to 117.0 ℃

物性(参考值)

熔点115 ℃

相关法规

RTECS#XT5490000
203895Sigma-AldrichBTS-CAS 1576-37-0-CalbiochemA potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC₅₀ = ~ 5 µM) and reversibly blocks the gliding motility.2165.23元/5 MG;   咨询

产品说明

一般描述

An aryl sulphonamide that acts as a potent inhibitor of Ca2+-stimulated myosin S1 actin-stimulated ATPase activity (IC50 = ~5 µM). Also blocks actin-stimulated ATPase activity with similar potency (IC50 = 5 µM). Reversibly blocks gliding motility of skeletal muscle myosin (IC50<2 µM). Less effective in suppressing contraction in rat myocardial and rabbit slow twitch muscle compared to skeletal muscle. Does not inhibit platelet myosin II.
A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ~ 5 µM) and reversibly blocks the gliding motility. It also weakens myosin’s interaction with F-actin. Much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Target IC50: ~5 µM against Ca2+-stimulated myosin S1 ATPase
Product does not compete with ATP.
Primary Target
Ca2+-stimulated myosin S1 ATPase
Cell permeable: no
Reversible: yes

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Cheung, A., et al. 2002. Nat. Cell Biol.4, 83.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C14H15NO2S
分子量261.34

产品性质

质量水平100
测定≥95% (HPLC)
形式crystalline solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性DMSO: 200 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3
InChI keyWTHKAJZQYNKTCJ-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9