基本信息

技术规格

物性(参考值)

安全信息

图形或危害标志
信号词	危险
危险性说明	H315 : 造成皮肤刺激。 H319 : 造成严重眼刺激。 H372 : 长期或反复接触会对器官造成损害。 H317 : 可能造成皮肤过敏反应。 H334 : 吸入可能导致过敏或哮喘病症状或呼吸困难。 H350 : 可能致癌。
防范说明	P501 : 将内装物/容器送到批准的废物处理厂处理。 P272 : 受沾染的工作服不得带出工作场地。 P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。 P270 : 使用本产品时不要进食、饮水或吸烟。 P202 : 在阅读并明了所有安全措施前切勿搬动。 P201 : 使用前取得专用说明。 P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P284 : [在通风不足的情况下]戴呼吸防护装置。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P308 + P313 : 如接触到或有疑虑：求医/就诊。 P337 + P313 : 如仍觉眼刺激：求医/就诊。 P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P304 + P340 : 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P333 + P313 : 如发生皮肤刺激或皮疹：求医/就诊。 P405 : 存放处须加锁。

基本信息

安全信息

图形或危害标志
提示语	Danger
危险说明	H315 H317 H319 H334 H335 H350
防范说明	P201 P261 P280 P305+P351+P338 P308+P313
WGK	3
TSCA	否

Technical Notes:

1.Nickel catalyst used in the N-he terocycle - directed cross- coupling of fluorinated arenes with organozinc reagents. Nickel catalyst used in the (E )-selective semihydrogenation of internal alkynes.

2.Nickel catalyst used in the borylation of halides and pseudohalides .

References:

1. Tetrahedron, 2014, 70, 4405.

2.J. Organomet. Chem., 2014, 749, 51.

3.J. Org. Chem., 2013, 78, 6427.

应用
Dichloro[bis(1,3-diphenylphosphino)propane]nickel(II) is used as an effective catalyst for Kumada coupling and Suzuki reactions. It also catalyzes other reactions to convert enol ethers, dithioacetals and vinyl sulfides to olefins. Further, it is used as a catalyst for preparation of block-copolythiophenes and solid state metathesis polycondensation.

备注
Moisture sensitive. Incompatible withstrong oxidizing agents.

基本信息

MDL
MFCD00015318

分子式
C₂₇H₂₆Cl₂NiP₂

分子量
542.03

熔点
213° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Insoluble in water.

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H317-H351-H335
Causes skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.Suspected of causing cancer.May cause respiratory irritation.

Precautionary Statements
P201-P261-P280-P305+P351+P338-P405-P501a
Obtain special instructions before use.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38-40-43
Irritating to eyes, respiratory system and skin.Limited evidence of a carcinogenic effect.May cause sensitization by skin contact.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

TSCA
否

基本信息

Ref#
29159

MDL
15318

分子式
C27 H26 Cl2 Ni P2

分子量
542.04

产品说明

应用

以下过程的催化剂：

• 嵌段共聚噻吩的合成
• 卤代芳烃与芳基硼酸的 Suzuki-Miyaura 交叉偶联反应
• 固态复缩聚反应
• 聚(3-烷氧基噻吩)的聚合
• 大环内酯类抗生素 aplyronine A 的 C1-C19 非对映选择性 Nozaki-Hiyama-Kishi 偶联反应
• 共轭聚合物的转移缩聚

包装

5, 25 g in glass bottle

基本信息

产品性质

安全信息

象形图
警示用语：	Danger
危险声明	H315 - H317 - H319 - H334 - H335 - H350
预防措施声明	P201 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类	Carc. 1A - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

基本信息

安全信息

图形或危害标志
提示语	Danger
危险说明	H315 H317 H319 H334 H335 H350
防范说明	P201 P261 P280 P305+P351+P338 P308+P313
WGK	3
TSCA	否

基本信息

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H317: May cause an allergic skin reaction. H319: Causes serious eye irritation. H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335: May cause respiratory irritation. H350: May cause cancer ..
防范说明	P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear . P281: Use personal protective equipment as required. P285: In case of inadequate ventilation wear respiratory protection. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313: IF exposed or concerned: Get medical advice/ attention. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P333 + P313: If skin irritation or rash occurs: Get medical advice/attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P342 + P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. P362: Take off contaminated clothing and wash before reuse. P363: Wash contaminated clothing before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .