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CAS: 156-54-7
分子式: C4H7NaO2
分子量: 110.09
熔点: 250-253℃
中文名称: 
丁酸钠
丁酸钠盐
英文名称: 
Butanoic acid sodium salt
Butanoic acid,sodium salt
Sodium butyrate
Butanoic acid, sodium salt
butyric acid, sodium salt
butyrate sodium
butyric acid sodium salt
sodium butanoate
sodium n-butyrate
sodium propanecarboxylate
推荐供应商
货号品牌产品名称规格包装、参考价格详情
S817488MACKLIN丁酸钠98%30元/25g;   50元/100g;   182元/500g;   578元/2.5kg;   1965元/10kg;   展开
储存：室温,干燥,密封
状态：白色到浅黄色粉末
S796204MACKLIN丁酸钠10mM in H2O185元/1ml;   展开
储存：-20°C
状态：液体
S0519TCISodium Butyrate>98.0%(T)215元/25G;   325元/100G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C4H7NaO2 = 110.09
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (吸湿)
Reaxys-RN3629439
PubChem物质ID87559080
MDL编号MFCD00002816

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %(calcd.on dried substance)
Drying lossmax. 5.0 %

物性(参考值)

熔点253 ℃
水溶性完全溶解

相关法规

RTECS#ET6400000
479725J&KSodium Butyrate98%89元/25G;   280元/100G;   761元/500G;   展开

基本信息

分子式C4H7NaO2
分子量110.09
熔点250-253
MDL编码MFCD00002816
Beilstein3629439
EINECS 编号205-857-6

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
H341
防范说明P261
P281
P305+P351+P338
WGK1
RTECSET6400000
TSCA是
A11079Alfa AesarSodium Butyrate98+%414元/5g;   514元/100g;   1251元/500g;   展开

应用
Decreases calcium release from intracellular stores. Inhibits histone deacetylase.Sodium butyrate is used in the treatment of human spinal muscular atrophy patients. Further, it is used in the determination of the role of histone acetylation in chromatin structure and function.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00002816

EINECS
205-857-6

分子式
C4H7NaO2

分子量
110.09

熔点
>300°

灵敏度
Hygroscopic. Ambient temperatures.

形态
Powder

溶解性
Soluble in water, dimethyl sulfoxide and ethanol. Insoluble in ether.

Beilstein
3629439

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
ET6400000

TSCA
是

C26319Alfa AesarButyric Acid Sodium Salt98%382元/5g;   471元/25g;   680元/100g;   2923元/500g;   展开

基本信息

Ref#
26319

MDL
2816

分子式
C4 H7 Na O2

分子量
110.09

B5887Sigma-AldrichSodium Butyrate≥98.5% (GC)546.28元/250 MG;   1850.18元/1 G;   4193.68元/5 G;   展开

产品说明

应用

丁酸钠已可用于：

  • 作为匀浆和免疫沉淀缓冲液的一种成分，在果蝇胚胎和昆虫s2细胞中抑制HDAC。
  • 以组蛋白脱乙酰酶抑制剂MDA-MB-231作为乳腺癌细胞株的抑制因子，采用细胞活力法和病毒复制法进行分析。
  • 提高生物反应器中中国仓鼠卵巢(CHO)细胞中重组组织纤溶酶原激活剂(t-PA)的产量。

包装

250 mg in glass bottle
1, 5 g in glass bottle

生化/生理作用

丁酸钠是一种短链脂肪酸，在毫摩尔范围内抑制组蛋白脱乙酰酶(HDAC)。减少细胞内Ca2+ 的释放。诱导数种细胞系的凋亡。丁酸钠诱导中国仓鼠卵巢(CHO)细胞和其他人类细胞系产生重组蛋白。丁酸钠影响细胞内的蛋白质组和基因表达通路。它抑制细胞周期相关基因，并修饰参与细胞代谢和凋亡的基因。

注意

吸湿

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
EC 号205-857-6
MDL编号MFCD00002816
PubChem化学物质编号24891873
NACRESNA.25

产品性质

质量水平200
生物来源synthetic (organic)
测定≥98.5% (GC)
形式powder
mp250-253 ℃ (lit.)
溶解性water: 100 mg/mL, clear to slightly hazy, colorless
储存温度room temp
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M
Gene Informationmouse ... ENSMUSG00000061062(15181)

安全信息

象形图GHS05GHS07
警示用语：Danger
危险声明H302 - H314
预防措施声明P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
07596SupelcoSodium Butyratecertified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland1692.88元/100MG;   展开

产品说明

一般描述

该认证标准物质(CRM)根据ISO/IEC 17025和ISO 17034进行生产和认证。该CRM可追溯来自NMI的原始材料，如NIST或NMIJ。
NMR 定量信息已包括在认证内容中。证书上已给出不确定性和失效日期。
在以下网址下载证书：http：//www.sigma-aldrich.com

应用

丁酸钠是丁酸的钠盐，具有强大的抗癌活性。它可以像组蛋白去乙酰化酶抑制剂一样发挥作用，并且已知在许多细胞系中影响基因表达和分化。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

法律信息

TraceCERT is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
EC 号205-857-6
MDL编号MFCD00002816
PubChem化学物质编号329748485
NACRESNA.24

产品性质

质量水平100
等级certified reference material
TraceCERT®
产品线TraceCERT®
保质期limited shelf life, expiry date on the label
储存条件under inert gas (Argon)
mp250-253 ℃ (lit.)
application(s)food and beverages
格式neat
储存温度2-8℃
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS05GHS07
警示用语：Danger
危险声明H302 - H314
预防措施声明P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
ARK2161SAFCSodium Butyrate4248.8元/250 G;   展开

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
EC 号205-857-6
MDL编号MFCD00002816
PubChem化学物质编号329773051
NACRESNA.21

产品性质

质量水平500
生物来源synthetic
形式powder
mp250-253 ℃ (lit.)
适用性suitable for manufacturing use
储存温度room temp
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M
303410Sigma-AldrichSodium Butyrate98%302.87元/5 G;   441.29元/100 G;   1353.13元/500 G;   展开

产品说明

一般描述

丁酸钠是丁酸的钠盐形式。它是一种已知抑制肿瘤细胞生长的天然化合物，并研究了其在人乳腺癌细胞系(MCF7)中的生物活性。丁酸钠可能是治疗人脊髓性肌萎缩症患者的有效药物。

应用

丁酸钠可作为反应剂，使用9-硼双环 [3.3.1] 壬烷(9-BBN)在 THF 中通过还原反应制备正丁醛。此外，还可通过还原氧化反应转化成丁醛硼烷和氯铬酸吡啶。采用基于离子液的氯亚胺试剂，丁酸钠通过光延反应与不同的醇发生反应生成酯。

包装

5, 100, 500 g in poly bottle

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
EC 号205-857-6
MDL编号MFCD00002816
PubChem化学物质编号24858121
NACRESNA.22

产品性质

质量水平200
测定98%
mp250-253 ℃ (lit.)
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M
Gene Informationmouse ... ENSMUSG00000061062(15181)

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319
预防措施声明P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
V900464Sigma-AldrichSodium ButyrateVetec™, reagent grade, 99%391.24元/5 G;   1356.79元/25 G;   展开

产品说明

包装

5, 25 g in glass bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
EC 号205-857-6
MDL编号MFCD00002816
PubChem化学物质编号329829865

产品性质

等级reagent grade
产品线Vetec™
测定99%
形式powder
mp250-253 ℃ (lit.)
溶解性water: 100 mg/mL, clear to slightly hazy, colorless
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS05GHS07
警示用语：Danger
危险声明H302 - H314
预防措施声明P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
567430Sigma-AldrichSodium Butyrate-CAS 156-54-7-CalbiochemA short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines by a p53-independent pathway.872.1元/250 MG;   展开

产品说明

一般描述

A short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines by a p53-independent pathway. Inhibits c-myc splicing and interferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Reduces histamine-induced calcium mobilization in C6 glioma cells. Down-regulates the activity of the serine/threonine protein kinase casein kinase II in HT29 cells.
A short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and interferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protein kinase casein kinase II in HT29 cells.

包装

250 mg in Glass bottle

生化/生理作用

Primary Target
Induce apoptosis
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Ou, H.C., et al. 1997. Neuroreport 8, 1375.
Russo, G.L., et al. 1997. Biochem. Biophys. Res. Commun. 233, 673.
Krupitza, G., et al. 1995. Carcinogenesis16, 1199.
Calabresse, C., et al. 1993. Biochem. Biophys. Res. Commun.195, 31.
Hague, A., et al. 1993. Int. J. Cancer55, 498.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C4H7NaO2
分子量110.09
MDL编号MFCD00002816

产品性质

质量水平200
测定≥98% (titration)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
颜色 white
溶解性water: 2 mg/mL
运输ambient
储存温度−20℃
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS05GHS07
警示用语：Danger
危险声明H302 - H314
预防措施声明P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
8.17500Sigma-AldrichSodium Butyratespecial quality410.99元/100 G;   展开

产品说明

分析说明

Assay (HClO₄): ≥ 98.5 %
Identity (IR): passes test
Appearance (white powder): passes test
Free acid/base: ≤ 2.0 ml
Heavy metals (Pb): ≤ 0.0005 %

基本信息

经验(实验)分子式C4H7NaO2
分子量110.09
MDL编号MFCD00002816
EC索引号205-857-6

产品性质

质量水平200
mp244 ℃
密度1.324 g/cm3 at 30 ℃
储存温度2-30℃
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS05GHS07
警示用语：Danger
危险声明H302 - H314
预防措施声明P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
8.20236Sigma-AldrichSodium Butyratefor synthesis2015.75元/250 G;   5467.25元/1 KG;   展开

产品说明

分析说明

含量(HClO₄)： ≥ 98.0 %
鉴定(IR)：通过测试

基本信息

经验(实验)分子式C4H7NaO2
分子量110.09
MDL编号MFCD00002816
EC索引号205-857-6

产品性质

质量水平200
mp244 ℃
密度1.324 g/cm3 at 30 ℃
储存温度2-30℃
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS05GHS07
警示用语：Danger
危险声明H302 - H314
预防措施声明P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
137127SAFCSodium ButyrateEMPROVE® EXPERT, USP4521.13元/250 g;   12237.9元/1 kg;   100621元/10 kg;   展开

产品说明

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
MDL编号MFCD00002816

产品性质

质量水平500
生物来源synthetic
agencyUSP
形式powder
包装pkg of 10kg (1371279010)
pkg of 1kg (1371271000)
pkg of 250g (1371270250)
pkg of 30kg (1371279030)
mp250-253 ℃ (lit.)
适用性suitable for manufacturing use
储存温度2-25℃
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319
预防措施声明P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
1613600USPSodium ButyrateUnited States Pharmacopeia (USP) Reference Standard3231.47元/25 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式CH3CH2CH2COONa
分子量110.09
Beilstein3629439
MDL编号MFCD00002816
PubChem化学物质编号329751106
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp250-253 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES string[Na+].CCCC([O-])=O
InChI1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI keyMFBOGIVSZKQAPD-UHFFFAOYSA-M

安全信息

象形图GHS07
警示用语：Warning
危险声明H302 - H315 - H319
预防措施声明P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
544147FluorochemSodium Butyrate98+%242元/100g;   展开

基本信息

CAS Number156-54-7
MDL NumberMFCD00002816
Melting Point250-253℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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